Top 9 Disease Management Software Companies With $1M–$5M Revenue (September 2026)

Atlanta, Georgia, United States

Developer of a cloud-based software solution designed to enable chronic disease management. The company's platform works within the EHR and combines patient-generated health data from connected devices with clinical data from the EHR to drive patient-specific clinical insights and actions and provides a risk stratification view, enabling clinicians to remotely monitor their patients' progress and virtually send encouragement or treatment adjustments when necessary.

Bangalore, Karnataka, India

Ai Health Highway is an AI-first company focused on making the screening of chronic diseases cost-effective at primary care clinics. They have developed an acoustic diagnostic device to screen, detect, and predict heart illnesses.

New York, New York, United States

Analyzing EHR and messaging data to predict disease before it occurs.

Denver, Colorado, United States

Provider of chronic care management products and services. The company's suite of applications provides patients with a platform to track their chronic care symptoms and treatment progress at the tip of their fingers. The applications and platform are easily customized to address specific requirements of chronic care management and reimbursement, while also removing financial and IT-integration barriers, enabling physicians and hospitals to fully leverage patient-reported data to improve clinical care and outcomes while maximizing reimbursement.

New York, New York, United States

AccurKardia is an ECG-led diagnostics software company transforming ECG signals into a broad biomarker and diagnostic tool for disease management in cardiology and beyond. Our mission is to improve patient outcomes and save lives on a global scale. Our flagship product, AccurECG™, is an FDA-cleared (Class II SaMD), cloud-based, device-agnostic software providing fully automated ECG interpretation, capable of detecting up to 13 arrhythmias. It assists cardiac monitoring companies in analyzing ECGs from holters, event recorders, and cardiac telemetry devices, significantly enhancing efficiency and patient care. Recently, AccurKardia reached a major milestone with the FDA Breakthrough Device Designation for our AI-driven ECG-based Aortic Valve Stenosis (AK-AVS) screening software. This achievement highlights our dedication to advancing early detection and precision medicine in cardiovascular care. We are also proud participants in the MedTech Innovator 2024 Cohort and the Heart & Brain Health Accelerator track, in collaboration with the American Heart Association’s Center for Health Technology and Innovation.

Stanford, California, United States

Remote monitoring for diabetes in pregnancy

New York, New York, United States

Telemedicine platform for chronic conditions like obesity

Palo Alto, California, United States

Caspar is a health platform that provides early detection of incidents and diseases using residents' medical & behavioral data throughout the home. With our 24/7 real-time health insights and alerts, clinical staff can become 10X more effective. With seven patents granted, our non-intrusive generative AI technology does not require cameras or wearables – yet it produces actionable data for better and more efficient care.

White Rock, Canada

Virtual Care for Type 2 Diabetes Reversal