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Top 20 Disease Management Software SaaS Companies in May 2026

As of May 2026, there are 20 SaaS companies in Disease Management Software. They have combined revenues of $809.1M and employ 1.1K people. They have raised $401.7M and serve - customers combined.

Disease Management Software encompasses tools designed to assist healthcare providers in managing and coordinating care for patients with chronic diseases. These software solutions enable the tracking of patient data, adherence to treatment plans, and overall disease management. They typically include features such as patient monitoring, care plan development, and proactive interventions that enhance the quality of care provided to individuals with chronic conditions. Common use cases for Disease Management Software include chronic disease tracking, risk stratification, and preventive care management. The software often integrates with electronic health records (EHR) to streamline data collection and access for healthcare professionals. Target users generally include healthcare providers, care coordinators, and health plan administrators seeking to improve patient outcomes and optimize the management of chronic diseases. Typical features of these solutions may include medication management alerts, patient engagement tools, and analytics to measure treatment effectiveness. By offering comprehensive support, Disease Management Software plays a crucial role in reducing hospital readmissions and improving the quality of life for patients with long-term health conditions.

Companies
20
Revenue
$809.1M
Funding
$401.7M
Employees
1.1K

Filters

Sorting: Highest -> Lowest

Filters

Top Disease Management Software Companies

Showing 10 of 20 companies ranked by annual revenue.

1
Somatus

McLean, Virginia, United States

Somatus is a leader in value-based kidney care working alongside health plans and providers to help prevent the progression of kidney disease.

Revenue
$750M
Customers
-
Year founded
2016
Funding
$400M
Team size
803
Growth
-
2
HealthSaaS

Portland, Oregon, United States

Provider of a chronic disease management platform intended to assist in patient monitoring and healthcare information management. The company's SaaS based healthcare management platform tracks and communicates medical data and historic reports, generates insights-based reports, monitors patient's adherence to health policies and enhances personalized care plans, enabling hospitals and clinics to monitor chronic diseases of patients who suffer from conditions such as diabetes, hypertension, heart failure, asthma, dementia and chronic pain.

Revenue
$16.9M
Customers
-
Year founded
2010
Funding
-
Team size
4
Growth
21%
3
Jana Care

Watertown, Massachusetts, United States

Jana Care develops and manufactures Aina Blood Monitoring Device, a novel-connected blood diagnostic device. The company focuses on chronic disease management through its digital health platform.

Revenue
$12.3M
Customers
-
Year founded
2011
Funding
-
Team size
78
Growth
-
4
myBiometry

Boston, Massachusetts, United States

A platform designed to remotely monitor and manage patients with chronic conditions, particularly asthma, using software and biomarker data generated from proprietary sensors.

Revenue
$7.7M
Customers
-
Year founded
2013
Funding
-
Team size
20
Growth
-
5
Rimidi

Atlanta, Georgia, United States

Developer of a cloud-based software solution designed to enable chronic disease management. The company's platform works within the EHR and combines patient-generated health data from connected devices with clinical data from the EHR to drive patient-specific clinical insights and actions and provides a risk stratification view, enabling clinicians to remotely monitor their patients' progress and virtually send encouragement or treatment adjustments when necessary.

Revenue
$3.4M
Customers
-
Year founded
2012
Funding
-
Team size
32
Growth
21%
6
Ai Health Highway

Bangalore, Karnataka, India

Ai Health Highway is an AI-first company focused on making the screening of chronic diseases cost-effective at primary care clinics. They have developed an acoustic diagnostic device to screen, detect, and predict heart illnesses.

Revenue
$3.1M
Customers
-
Year founded
2018
Funding
-
Team size
24
Growth
-
7
Quadrant Health

New York, New York, United States

Analyzing EHR and messaging data to predict disease before it occurs.

Revenue
$3M
Customers
-
Year founded
2020
Funding
-
Team size
20
Growth
-
8
cliexa

Denver, Colorado, United States

Provider of chronic care management products and services. The company's suite of applications provides patients with a platform to track their chronic care symptoms and treatment progress at the tip of their fingers. The applications and platform are easily customized to address specific requirements of chronic care management and reimbursement, while also removing financial and IT-integration barriers, enabling physicians and hospitals to fully leverage patient-reported data to improve clinical care and outcomes while maximizing reimbursement.

Revenue
$2.9M
Customers
-
Year founded
2015
Funding
$1.7M
Team size
16
Growth
63.73%
9
AccurKardia

New York, New York, United States

AccurKardia is an ECG-led diagnostics software company transforming ECG signals into a broad biomarker and diagnostic tool for disease management in cardiology and beyond. Our mission is to improve patient outcomes and save lives on a global scale. Our flagship product, AccurECG™, is an FDA-cleared (Class II SaMD), cloud-based, device-agnostic software providing fully automated ECG interpretation, capable of detecting up to 13 arrhythmias. It assists cardiac monitoring companies in analyzing ECGs from holters, event recorders, and cardiac telemetry devices, significantly enhancing efficiency and patient care. Recently, AccurKardia reached a major milestone with the FDA Breakthrough Device Designation for our AI-driven ECG-based Aortic Valve Stenosis (AK-AVS) screening software. This achievement highlights our dedication to advancing early detection and precision medicine in cardiovascular care. We are also proud participants in the MedTech Innovator 2024 Cohort and the Heart & Brain Health Accelerator track, in collaboration with the American Heart Association’s Center for Health Technology and Innovation.

Revenue
$1.5M
Customers
-
Year founded
2019
Funding
-
Team size
14
Growth
-
10
Malama Health

Stanford, California, United States

Remote monitoring for diabetes in pregnancy

Revenue
$1.5M
Customers
-
Year founded
2022
Funding
-
Team size
10
Growth
-

Inclusion Criteria

- Must provide tools for tracking chronic disease management and patient progress - Should include features for care plan development and monitoring - Must enable integration with electronic health records or similar systems - Should support proactive patient engagement and communication - Must offer analytics or reporting capabilities to evaluate treatment outcomes - Not just for general health management; must focus specifically on chronic disease management