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Top 405 SaaS Companies in Chicago, United States, October 2026

As of October 2026, there are 405 SaaS companies based in Chicago. They have combined revenues of $10.4B and employ 60.1K employees. They've raised $6.6B in capital and serve 39.4M customers combined.

Companies
405
Revenue
$10.4B
Funding
$6.6B
Employees
60.1K

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Top SaaS Companies in Chicago

Showing 10 of 405 companies ranked by annual revenue.

1Vestian logo
Vestian

Chicago, Illinois, United States

A global real estate advisory firm offering a comprehensive suite of services, including portfolio management, brokerage advisory and project management

Revenue
$761.3M
Customers
-
Year founded
2016
Funding
-
Team size
511
Growth
-
2DOE Media logo
DOE Media

Chicago, Illinois, United States

Direct response advertising and retention marketing agency providing sophisticated solutions to clients ranging from startups to Fortune 500 brands

Revenue
$700M
Customers
-
Year founded
2018
Funding
-
Team size
71
Growth
-
3Tempus AI logo
Tempus AI

Chicago, IL, United States

Tempus is making precision medicine a reality by applying AI in healthcare, deriving insights from our expansive library of clinical data and molecular data. We enable physicians to make real-time, data-driven decisions to deliver personalized care and targeted therapies for patients through our analytical machine learning platform that uses the power of artificial intelligence in healthcare. We also work with partners to facilitate discovery, development, and delivery of optimized therapeutic options for patients through distinctive solution sets. Our mission is for each patient to benefit from the treatment of others who came before by providing the healthcare industry tools that learn as we gather more data. It’s About Time. For more information, visit tempus.com and follow us on Twitter (@TempusLabs).

Revenue
$316.1M
Customers
-
Year founded
2015
Funding
-
Team size
2.9K
Growth
-
4ActiveCampaign logo
ActiveCampaign

Chicago, Illinois, United States

provider of marketing automation and customer experience automation (CXA) software

Revenue
$290.5M
Customers
145K
Year founded
2003
Funding
$360M
Team size
865
Growth
-
5Basecamp logo
Basecamp

Chicago, Illinois, United States

a project management and team communication platform

Revenue
$280M
Customers
252K
Year founded
1999
Funding
-
Team size
80
Growth
-
6IRI logo
IRI

Chicago, Illinois, United States

IRI is a leading provider of big data, predictive analytics and forward-looking insights that help CPG, OTC healthcare, retailers and media companies to grow their businesses. With the largest repository of purchase, media, social, causal and loyalty data, all integrated on an on-demand cloud-based technology platform, IRI guides its clients around the world in their quests to remain relentlessly relevant, capture market share, connect with consumers and deliver market-leading growth.

Revenue
$268.5M
Customers
-
Year founded
-
Funding
-
Team size
2.4K
Growth
-
7Relativity logo
Relativity

Chicago, Illinois, United States

Relativity is a technology company that provides e-discovery software solutions for managing electronic data during legal proceedings.

Revenue
$235.9M
Customers
-
Year founded
2001
Funding
$125M
Team size
1.8K
Growth
-
8Keeper Security logo
Keeper Security

Chicago, Illinois, United States

Keeper Security is a Chicago-based cybersecurity company founded in 2011 by Darren Guccione and Craig Lurie. The company develops Keeper, a password manager and secure digital vault, along with KeeperChat, an encrypted messaging application, and additional security products including secure digital file storage and BreachWatch, a dark web monitoring service. As of late 2018, Keeper Security reported more than 15 million users across more than 100 countries, with thousands of new users added to the platform each day. The company serves both individual consumers and businesses, with 85 percent of its business-to-business revenue coming from organizations it classifies as small and medium-sized businesses, defined as companies with fewer than 1,000 employees. Keeper Security has been entirely bootstrapped since inception, with Guccione seed-funding the company and the founders reinvesting profits into growth. The company reported being profitable as of 2018, with a 90 percent or better annual subscription retention rate and a team that grew from roughly 35 people in 2016 to approximately 140 by late 2018.

Revenue
$225M
Customers
95K
Year founded
2011
Funding
$60.3M
Team size
344
Growth
-
9Hugo logo
Hugo

Chicago, Illinois, United States

Hugo is transforming the future of a continent by re-envisioning the future of its work. We exist to provide BPO excellence to our customers by investing heavily in the very best of African talent. African communities currently reap less than 2% of a BPO market worth a staggering $430 billion annually. We are changing this. Specializing in digital and AI operations, omnichannel customer support, and trust and safety solutions for some of the world’s largest tech and media companies, we are providing the continent’s university-educated youth with the skills necessary to build a meaningful career in the global digital economy. All whilst delivering industry-beating excellence for our clients. As a culture, we’re Silicon Valley meets ECOWAS — English et en Français. We’re smart, dynamic, and ambitious. And we’re on a mission to win for our clients and for our people

Revenue
$220.1M
Customers
-
Year founded
2017
Funding
-
Team size
2K
Growth
-
10Quinnox logo
Quinnox

Chicago, Illinois, United States

Provider of information technology services intended to address complex issues and capitalize on opportunities to help deliver better outcomes. The company's services use digital components such as analytics, mobility, social media, and smart-embedded devices to change customer experience journeys and internal processes and offer end-to-end implementation, development and support services in the select industries of banking and financial services, retail and manufacturing, enabling customers transform technology portfolios from systems of record to launch pads of innovation.

Revenue
$213.9M
Customers
-
Year founded
1999
Funding
-
Team size
1.7K
Growth
-