Top 222 SaaS Companies in Maryland, United States, May 2026

Rockville, Maryland, United States

InfoPro Systems Inc. is a software development and consulting firm specializing in designing systems that collect, process and distribute clinical and research medical science data. InfoPro has executed a series of large-scale projects for health related studies and clinical trials for the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) as well as for commercial clients. The majority of projects were based on effective design of the metadata for health studies to dynamically drive data collection, data review, analyses and publishing. This approach also helps bring data and process transparency to non-IT users, including scientists and health content and domain experts.

Baltimore, Maryland, United States

Welcome to the nope. movement. More than just an art and apparel brand, nope. embodies a bold stand against the ordinary. Founded by visionary artist Ethan Peterson, nope. serves as a beacon for those who dare to break free from the norm. Inspired by Ethan's own struggles with conformity and his journey to embrace his true self, nope. was created to inspire and uplift those who seek meaning beyond the surface. In a world that constantly pushes uniformity, nope. stands as a symbol of unflinching individuality. The mission extends beyond art – it’s about empowering individuals to navigate their personal journeys with unrestrained creativity and authenticity. Through unique and expressive products and services, nope. encourages an unapologetic declaration of identity. nope. isn’t just a brand; it’s a declaration to walk your path with fearless conviction.

Bethesda, Maryland, United States

SimTek is the world's easiest to use Learning Management System For training professionals who need a trusted vendor with deep domain expertise, SimTek by AWS Cloud provides a cloud-based learning management solution (LMS) that unifies virtual classroom, mobile, social and eCommerce capabilities in a single, secure, and scalable platform that can meet any organization's training needs. With SimTek LMS, you can engage learners anytime through native apps for Android and iOS, extend your ecosystem by using pre-packaged connectors and REST APIs, and protect your data through enterprise-grade security. SimTek LMS is used for employee training, customer training, compliance training, and partner training.

Chevy Chase, Maryland, United States

EdgarStat® is an online database of listed global company financials and transfer pricing analytics software. EdgarStat is useful to find comparable companies and determine a reliable arm's-length range for all US and OECD profit indicators, including gross profit margin, Berry ratio, operating profit margin and return on operating assets. EdgarStat’s interactive software tools enable users to calculate interquartile ranges, make assets-based adjustments, and perform regression functions to compute more reliable profit indicators.

Bethesda, Maryland, United States

Developer of a platform created to provide the most relevant and contextual interactions to drive individual action. The company's platform uses the power of personalization and predictive analytics to facilitate contextually relevant two-way conversations at scale between brands and their entire audience across device and platform, enabling clients to get data-driven advantage by humanizing data and insights.

Columbia, Maryland, United States

The global leader in secure collaboration, cloud storage and data access management. HighSide enables the modern business, addressing challenges in productivity, data sharing and engagement typically stymied by data security, compliance and data access requirements

Centreville, Maryland, United States

CHALEX corp offers the SmartFlo SaaS server, a web-based workflow, digital asset management system for the enterprise. The software helps teams manage high volume distributed brand planning and production projects. CHALEX SmartFlo software enables smart sourcing of projects jobs and tasks while managing the import and creation process for the lifecycle of digital assets and their brands.

Bethesda, Maryland, United States

Market implementation services solutions the same way you do your software product! ‣ Enable customers to get implementation services from your certified partners in minutes instead of weeks ‣ Reduce partner services costs and prices by 66% ‣ Integrate implementation services into your lifecycle marketing ‣ Know and show the impact of partner implementation services on customer behavior Nearly every service industry has already adopted the productized services model because it’s what buyers demand. It’s time for software companies to do the same! LEARN MORE at Figfy.io

Bethesda, Maryland, United States

Update: MindX and its team have been acquired by Blackrock Neurotech, and you can follow our continued work there! At MindX, we're combining neurotechnology, augmented reality and artificial intelligence to create a "look-and-think” interface for next- generation spatial computing applications.

Silver Spring, Maryland, United States

Audienti is a next-generation Conversational-Intent Marketing (CIM) platform for sales and marketing teams. It helps you engage sooner, so you can help prospects along their buyer journey. Because it’s conversation-based, Audienti eliminates cold emailing and outreach. You're always replying to a prospect instead of doing cold outreach. It's multi-channel, so it works for B2B and B2C markets. And, its data integrates with your current MarTech stack. The early bird gets the worm. Shouldn't you be the early bird?