Top 57 SaaS Companies in New Hampshire, United States, May 2026

Portsmouth, New Hampshire, United States

At Bottomline, we help businesses pay and get paid. As a trusted partner to banks, corporates, and financial institutions worldwide, we deliver secure, scalable, and innovative solutions that simplify complex payment workflows, reduce fraud risk, and drive operational efficiency. With decades of expertise in financial messaging, cash management, and digital banking, our SaaS platforms and services are built to meet the evolving needs of modern finance teams. Whether it's automating B2B payments, streamlining compliance, or enabling real-time visibility into cash flow, Bottomline is committed to making business payments seamless and secure. We serve over 1,200 financial institutions and 10,000 businesses globally, helping them navigate the future of payments with confidence.

Manchester, New Hampshire, United States

Sequel Med Tech is a healthcare technology company focused on diabetes management, developing transformative drug-delivery advancements to improve the health and lives of people with diabetes.