As of May 2026, there are 120 SaaS companies based in South Carolina. They have combined revenues of $678.1M and employ 3.7K employees. They've raised $56.2M in capital and serve 34.8K customers combined.
Sorting: Highest -> Lowest
Showing 10 of 16 companies ranked by annual revenue.
Mount Pleasant, South Carolina, United States
Health care provider specializing in providing perfusionist staffing to hospitals and health systems using heart-lung bypass equipment
North Charleston, South Carolina, United States
Provider of comprehensive IT support, cloud management, security and managed services to SMBs and education clients across the U.S
Charleston, South Carolina, United States
A real estate technology company offering repair, renovation and maintenance services through a one-stop-shop platform
Rock Hill, South Carolina, United States
SPAN Enterprises is a software company based in the small, historic town of Rock Hill, South Carolina, proudly creating jobs in the USA since 2009. Currently, SPAN has over 14 industry-leading, cloud-based applications across a variety of different industries. From ACA filers, to yoga instructors, to long-haul truckers, SPAN has created and provided software for the needs of innumerable clients, all while maintaining impeccable customer service and support. SPAN Enterprises is not your average software company; it celebrates tradition and stays connected to its roots while also forging new paths in pursuit of intuitive, cutting-edge software solutions. Want to know more about what we have to offer? Take a look and see for yourself on the SPAN website.
Daniel Island, South Carolina, United States
At IndySoft, we empower businesses by delivering innovative, scalable solutions for calibration, asset, and maintenance management. With over 25 years of industry expertise, our software enables companies across various sectors—ranging from aerospace to manufacturing—to streamline their operations, enhance efficiency, and ensure compliance with rigorous industry standards. Our highly configurable platform is designed to adapt to the unique workflows of each client, offering robust tracking, reporting, and automation tools that improve accuracy and reduce downtime. Whether you manage a small lab or a global enterprise, IndySoft provides the tools you need to optimize your processes and drive growth. Join the thousands of organizations worldwide that trust IndySoft to enhance their operational excellence.
Charleston, South Carolina, United States
Sprockets is a SaaS company with a sophisticated solution to hiring the right applicants.
Charleston, South Carolina, United States
Our team is comprised of eCommerce and analytics experts from a variety of brand and agency backgrounds. Founded in 2017, Elevar is the leading analytics and tracking platform built exclusively to help ensure direct-to-consumer brands on Shopify have a data foundation they can trust and scale with. As an official Shopify Plus and Facebook Marketing Partner, we bridge the gap between marketers and engineers with some of the fastest growing brands. Chances are if there is a problem you’re trying to solve with your own analytics and marketing tags we’ve fixed it. Learn more about us: https://www.getelevar.com/
Fort Mill, South Carolina, United States
Developer of a request for proposal, qualification and Information platform designed to optimize workflow and maximize outcomes. The company's platform manages all RFP opportunities while provides efficiencies in responding, managing team and scoring responders, enabling companies to streamline their RFP process, save time and achieve better outcomes.
Columbia, South Carolina, United States
Financial firm helping people plan for retirement, creating custom strategies using a variety of investments, products and services
Each Tuesday, we reverse-engineer a real SaaS company's revenue, profit, CAC, funnels, and its top growth tactic.
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