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Top 149 SaaS Companies in Missouri, United States, May 2026

As of May 2026, there are 149 SaaS companies based in Missouri. They have combined revenues of $5.2B and employ 12.2K employees. They've raised $852.8M in capital and serve 740.5K customers combined.

Companies
149
Revenue
$5.2B
Funding
$852.8M
Employees
12.2K

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Top SaaS Companies in Missouri

Showing 10 of 22 companies ranked by annual revenue.

1
Well Principled

St. Louis, Missouri, United States

Well Principled is an A.I

Revenue
$10M
Customers
-
Year founded
2019
Funding
-
Team size
8
Growth
785.77%
2
US Cloud

Saint Louis, Missouri, United States

Provides reputable Microsoft enterprise support to clients world-wide. Enables Microsoft Premier (Unified) Support customers to enjoy ultra-responsive support from US citizens, saving 30-60% on support costs and freeing up funds to drive innovation

Revenue
$10M
Customers
-
Year founded
2006
Funding
-
Team size
124
Growth
-
3
Cryptotrader

Kansas, Missouri, United States

Automates Cryptocurrency Taxes

Revenue
$10M
Customers
7K
Year founded
2017
Funding
-
Team size
18
Growth
69.55%
4
Mid-West Computech

Columbia, Missouri, United States

Accomplished executive with 25 years of general management, P&L responsibility, leadership and sales experience in the highly competitive automotive manufacturing industry. Proven track record of driving business strategy growth, profitability and customer satisfaction. Excels at building strong relationships with clients, partners and employees.

Revenue
$9.8M
Customers
-
Year founded
1982
Funding
-
Team size
26
Growth
134.84%
5
NextPage Kansas City

Kansas City, Missouri, United States

Engaging with your clients, customers, and prospects takes a multipronged strategic approach. NextPage is a total marketing solutions company combining traditional print expertise with personalized digital marketing techniques to drive results. Since 1988, NextPage specializes in business-building ideas and solutions utilizing our UNMATCHED EXPERIENCE in: • Direct Mail Automation & Printing • Commercial Printing • Digital Printing • Data Marketing • Digital Marketing • Studio Marketing Portal • Data Modeling & Predictive Analytics • Kitting & Fulfillment • Integrated Marketing • Promotional Products + Other One-to-One Experiences Leading Companies Turn to Us for Custom Printing & Marketing Solutions To Create Business-Building Solutions. NextPage Industry Experience: • Advertising Agencies • Financial Services | Banks | Credit Unions • Healthcare | Hospitals – HIPAA Compliant • Insurance • Non-Profit Every day, we create exceptional experiences by reinventing how our customers engage with their customers. Most of our customers have a few key points in common – they maintain extensive data on their customers, they require critical communication touches to their customers, and they need flawless execution. We are CREATORS of ✔Smart, ✔Efficient, ✔One-to-One, ✔Brand-to-Human Connections. We exist to create: • The right business-building strategies in partnership with our clients’ strategic marketing plans • Innovative, efficient, & affordable solutions • Positive results We Are Driven By Accountability and Results • We do our best work when we are an extension of your team • We serve our customers best when we have a seat at the table Our relentless focus on performance and positive results for our customers motivates us to provide smart, effective ideas and solutions. Visit our website https://gonextpage.com/ or contact us at 800.660.0108 for more information about how to take YOUR company to the Next Page.

Revenue
$9.4M
Customers
-
Year founded
1988
Funding
-
Team size
85
Growth
-
6
KnowledgeLake

Town and Country, Missouri, United States

KnowledgeLake’s Intuitive AI™ Powered Enterprise Automation platform enables organizations streamline their operations by automating the capture, processing, and management of content. The company's unique 4-point solution increases operational efficiency by integrating Adaptive IDP, Workflow Automation, Intelligent RPA & Content Management into a single AI powered platform. KnowledgeLake’s digital labor amplifies human work and lowers costs — all with easy consumption pricing. Central to its innovation is the concept of Synthetic Labor™, which integrates artificial intelligence to take over high-volume, repetitive tasks, allowing human workers to focus on strategic and value-added activities. This unique approach blends human oversight with AI capabilities, creating seamless workflows that adapt to the complexities of modern business environments. KnowledgeLake's solutions are designed to improve data accuracy, reduce operational costs, and enable faster decision-making, particularly within industries that handle large volumes of content, such as financial services, government, and healthcare. By incorporating Synthetic Labor into its platform, KnowledgeLake continues to be at the forefront of the digital transformation, driving real-world impact for its clients with AI-driven automation and a commitment to innovation. With two million users, the company has earned numerous accolades, including five ‘Microsoft Partner of the Year’ awards. For more information, visit knowledgelake.com.

Revenue
$8.3M
Customers
-
Year founded
1999
Funding
-
Team size
75
Growth
-
7
VINCUE

Kansas City, Missouri, United States

VINCUE™ is transforming the retail automotive software industry by providing dealers with a new innovative end-to-end inventory lifecycle management and market pricing solution giving dealers access to real-time data and tools in a single system to stock smarter, increase turn, compete effectively, and above all else - maximize profits.

Revenue
$8.1M
Customers
-
Year founded
2015
Funding
-
Team size
74
Growth
-
8
Crema

Kansas City, Missouri, United States

Crema is a design and technology consultancy that helps companies build the custom software they need to compete in today’s market. Our product teams blend business strategy and technical expertise to create solutions for our clients’ most pressing needs. Whether companies need to automate processes, make more data-driven decisions, or prep for growth, they come to our team of experts to craft a world-class product experience. We offer a wide range of services from problem framing and business strategy to UX/UI design and development. Crema is not a "dev shop" that churns code without regard for the outcomes that follow. Our clients will tell you that our greatest service is not only providing high quality designs and code, but also bringing the critical thinking, collaboration, and spirit of partnership that carry the experience beyond its intended impact. Unlike other product agencies, our approach is highly bespoke and strategic. Our methodology is based around small cross-functional teams collaborating towards business outcomes. This agile-oriented model minimizes distractions, emphasizes impact, and provides clear communication paths to focus on the work at hand.

Revenue
$7.2M
Customers
-
Year founded
2009
Funding
-
Team size
65
Growth
-
9
1905 New Media

St. Charles, Missouri, United States

An integrated marketing communications firm that offers branding, digital marketing, custom website and app development, public relations and commercial printing

Revenue
$7M
Customers
-
Year founded
1905
Funding
-
Team size
28
Growth
-
10
Colibri Real Estate

St. Louis, Missouri, United States

Since 1996 we have helped hundreds of thousands of real estate agents launch their careers through our online course platform and real estate exam prep program.

Revenue
$6.9M
Customers
-
Year founded
-
Funding
-
Team size
63
Growth
-