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Top 149 SaaS Companies in Missouri, United States, May 2026

As of May 2026, there are 149 SaaS companies based in Missouri. They have combined revenues of $5.2B and employ 12.2K employees. They've raised $852.8M in capital and serve 740.5K customers combined.

Companies
149
Revenue
$5.2B
Funding
$852.8M
Employees
12.2K

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Top SaaS Companies in Missouri

Showing 10 of 56 companies ranked by annual revenue.

1
Directorie

Chesterfield, Missouri, United States

Offering director-level thinking on any commercial life science pharmaceutical brand, such as marketing, peer-to-peer and patient initiatives

Revenue
$5M
Customers
-
Year founded
2018
Funding
-
Team size
30
Growth
-
2
Text In Church

Parkville, Missouri, United States

At Text In Church, we believe church communication shouldn’t be difficult. Every church wants to connect with guests, engage their congregation, and build lasting relationships—but without the right tools, it can be overwhelming. That’s why we provide simple yet powerful communication solutions designed specifically for churches. Each week, over 35,000 church leaders rely on Text In Church to communicate effectively and ensure no one slips through the cracks. What Does Text In Church Do? Text In Church equips churches with text messaging, email, and calling tools that make follow-up easy, ensure consistent communication, and foster deeper engagement. • Text Messaging – Send personalized and automated text messages to first-time guests, members, and ministry teams. Follow up instantly, send event reminders, and keep your church engaged. • Email – Craft beautiful, effective emails to communicate with your congregation. Schedule follow-ups, send weekly updates, and stay in touch with ease. • Calling – Set up a dedicated church phone number, leave pre-recorded voicemails, and manage outreach effortlessly. More Than Just Software Text In Church is more than a communication platform—it’s a ministry partner. The right tools are essential, but so are proven strategies to make them effective. That’s why Text In Church provides: • Pre-built templates and automated workflows for seamless guest follow-up, event reminders, and member engagement. • Best practices and coaching to help churches maximize their communication efforts. A Growing, All-in-One Communication Solution In 2024, Text In Church acquired PastorsLine, expanding its messaging solutions and enhancing its ability to serve more churches with innovative communication tools. By combining powerful technology with best practices, Text In Church empowers churches to reach more people, build stronger relationships, and grow their impact. Learn more at www.textinchurch.com.

Revenue
$5M
Customers
-
Year founded
-
Funding
-
Team size
27
Growth
-
3
Timmermann Group

St. Louis, Missouri, United States

A full-service digital marketing agency with over twenty years of experience that helps companies create conversions through compelling creative

Revenue
$5M
Customers
-
Year founded
2003
Funding
-
Team size
36
Growth
-
4
ATB Technologies

Chesterfield, Missouri, United States

Managed service provider and program development company providing IT services to small and midsize organizations in the Midwest

Revenue
$5M
Customers
-
Year founded
2002
Funding
-
Team size
37
Growth
-
5
PopBookings

Kansas City, Missouri, United States

PopBookings is an online software that makes the process of booking and communicating with event staff simple by streamlining every step on one easy platform. If you or your company could benefit from implementing PopBookings, contact us at [email protected]. Or schedule a free demo here: popbookings.com/demo

Revenue
$5M
Customers
-
Year founded
2014
Funding
-
Team size
45
Growth
-
6
Money Tree Lead Systems

Springfield, Missouri, United States

Provides software-as-a-service lead generation and customer relationship management to real estate agents

Revenue
$4.9M
Customers
-
Year founded
2013
Funding
-
Team size
43
Growth
-
7
Gateway X

Saint Louis, Missouri, United States

Gateway X is a holding company that builds, buys and invests in market-leading DTC (direct to consumer) companies. Our purpose is to help people learn, grow and be the best versions of themselves through the journey of entrepreneurship. We value being fast, data-driven, customer centric and adaptable in our approach. We are committed to building one of the most important companies in the DTC revolution. We will be a profitable, long-term organization with an extraordinary culture and several unique winning brands.

Revenue
$4.8M
Customers
-
Year founded
2021
Funding
-
Team size
8
Growth
-
8
Secure Passage

Kansas City, Missouri, United States

Secure Passage was born from a simple truth: today’s risks don’t live in silos. Physical identities, digital activity, video, sensors, and intelligence all blend into one operational picture—and security must, too. Formerly Haystax, we’ve evolved our name and mission to reflect what we actually deliver: a clear, unified passage through complexity. With the Truman Identities platform and our Operational Intelligence Platform (OIP), we’re building software and solutions that help organizations see more, connect more, and protect what matters most. For more than 25 years, our team has supported: • School & Campus Safety • Public Safety Agencies • Critical Infrastructure • Event & VIP Risk Management • Enterprise Threat & Intelligence Teams • Behavioral & Physical Security Assessments • Large-scale Data Aggregation and Correlation Secure Passage: Elemental to Your Security.

Revenue
$4.3M
Customers
-
Year founded
2012
Funding
-
Team size
39
Growth
-
9
Emfluence

Kansas City, Missouri, United States

We believe that knowing who your customers are means more than tossing them into groups based solely on their job title or gender. Your customers are people, and they deserve to be treated like the quirky individuals they are. But marketing isn’t just about knowing who to talk to—you have to know when to speak up and enter the conversation. Our aim is to transform you into a nimble marketer, to arm you with the game plan and insight you need to create your own moments. As much as we love conversations, we should admit that we’re also sticklers for details. Roadmaps, agendas, plans, strategy, budget—we geek out on executing to a plan. You’ll never have to guess what we’re executing, when we’re executing it, or why we’re executing it. That doesn’t mean we’re going to abandon you with a dashboard full of percentages and pretty pie charts. Numbers can be powerful, but only if you know what they mean. The numbers we give you are directly tied to your goals. Conversions, clicks, impressions, opens—we’ll help you define what matters so that you can focus on capitalizing on the results. And hey, it’s okay if you’re in it for the money.

Revenue
$4.3M
Customers
-
Year founded
2003
Funding
-
Team size
39
Growth
-
10
Global Vision Technologies

St Louis, Missouri, United States

Global Vision Technologies, Inc., (GVT) is a leading provider of web-based, information management solutions that help healthcare organizations and human services agencies better serve the individuals, families, patients and communities under their care. GVT's mission is to enrich the lives of the individuals we work with by solving the impossible. Through technology and expertise, we close the gap between human, health and services. We do this by providing expertise in 3 specific areas: DATA · Giving you the tools to collect the data you need. · Providing intuitive search functions to find the data you need. · Empowering you with personalized dashboards and reports that make the data meaningful. PLATFORM · A true development platform · Configurable and customizable to meet your individual needs. · Intuitive workflow to drive daily staff productivity and better client outcomes PROTECTION · Best-in-class personalized support, training and protection · 99.9% uptime, consistent, steady and stable · State of the art security protocols, HIPAA compliant, front end and back end Our main product lines are FAMCare case management software for social workers and ClincialPURSUIT patient registry software - a strategic database solution that helps organizations run patient research studies.

Revenue
$4.2M
Customers
-
Year founded
1997
Funding
-
Team size
38
Growth
-
Missouri, United States SaaS Companies | GetLatka