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Top 16 SaaS Companies in St Louis, United States, May 2026

As of May 2026, there are 16 SaaS companies based in St Louis. They have combined revenues of $438.7M and employ 2.2K employees. They've raised $14.3M in capital and serve 3.2K customers combined.

Companies
16
Revenue
$438.7M
Funding
$14.3M
Employees
2.2K

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Top SaaS Companies in St Louis

Showing 10 of 8 companies ranked by annual revenue.

1
TRIBUS Group

St Louis, MO, United States

TRIBUS Group is the holding company for various real estate technology brands such as TRIBUS, Solid Earth, Destination Coaching, Displet, and Nautilent.

Revenue
$4.3M
Customers
-
Year founded
2009
Funding
-
Team size
39
Growth
-
2
Global Vision Technologies

St Louis, Missouri, United States

Global Vision Technologies, Inc., (GVT) is a leading provider of web-based, information management solutions that help healthcare organizations and human services agencies better serve the individuals, families, patients and communities under their care. GVT's mission is to enrich the lives of the individuals we work with by solving the impossible. Through technology and expertise, we close the gap between human, health and services. We do this by providing expertise in 3 specific areas: DATA · Giving you the tools to collect the data you need. · Providing intuitive search functions to find the data you need. · Empowering you with personalized dashboards and reports that make the data meaningful. PLATFORM · A true development platform · Configurable and customizable to meet your individual needs. · Intuitive workflow to drive daily staff productivity and better client outcomes PROTECTION · Best-in-class personalized support, training and protection · 99.9% uptime, consistent, steady and stable · State of the art security protocols, HIPAA compliant, front end and back end Our main product lines are FAMCare case management software for social workers and ClincialPURSUIT patient registry software - a strategic database solution that helps organizations run patient research studies.

Revenue
$4.2M
Customers
-
Year founded
1997
Funding
-
Team size
38
Growth
-
3
JW Software

St Louis, Missouri, United States

Owner and operator of a management software technology company intended to focus on development and support of product-based insurance technology. The company's cloud-based technology includes file handler and policy handler which manage policies and insurance claims, enabling clients to streamline operations, increase production and lower costs.

Revenue
$3.2M
Customers
-
Year founded
1989
Funding
-
Team size
37
Growth
33.38%
4
Tallyfy

St Louis, Missouri, United States

Developer of a cloud based workflow automation software designed to track and improve recurring workflows in real-time. The company's software specializes in client onboarding, customer success, business process management, workflow, process improvement and compliance, enabling organizations to prevent human errors and streamline business processes.

Revenue
$2.8M
Customers
-
Year founded
2012
Funding
-
Team size
18
Growth
97.81%
5
Aggio

St Louis, Missouri, United States

Developer of a marketing and sales enablement software built for the agriculture industry. The company's software offers an executive dashboard to measure - price, volume, market share, market health, facilitates multiple data sources summarized in a few key business indicators for better, faster decision making, dynamic yield & grower profitability calculators, real-time tracking of daily sales, orders, inventory position and progress against targets and enterprise data integration, enabling marketing and sales teams to harmonize data, consolidate planning assumptions and turn insights into actions.

Revenue
$2.8M
Customers
-
Year founded
2016
Funding
-
Team size
9
Growth
31.85%
6
Service Works

St Louis, Missouri, United States

Complete platform for running service business from anywhere with enterprise level features and the lowest price on the market. Create estimates & jobs, schedule & dispatch, invoice, manage inventory , purchase order and more. Learn how you can optimize your business and win more customers at https://service.works

Revenue
$2.6M
Customers
-
Year founded
2016
Funding
-
Team size
24
Growth
-
7
6Storage

St Louis, Missouri, United States

6Storage - The self storage software trusted and used by storage owners and operators across 40+ countries. We offer self storage website design, marketing and SEO, 6Security cloud-based access controls, and 6Storage tenant protection plans to automate and streamline your day-to-day storage management operations.

Revenue
$2M
Customers
-
Year founded
2007
Funding
-
Team size
18
Growth
-
8
ClearSight Health Inc.

St Louis, Missouri, United States

ClearSight Health is dedicated to driving growth and efficiency in the medical device industry by providing cloud-based tools to commercial teams to make their jobs faster and more efficient. Through finding new physician targets and managing those relationships, ClearSight Health is the first enablement solution created for the medical device representative.

Revenue
$1.3M
Customers
-
Year founded
2020
Funding
-
Team size
12
Growth
-
St Louis, United States SaaS Companies | GetLatka