As of May 2026, there are 843 SaaS companies based in Massachusetts. They have combined revenues of $26.5B and employ 134.9K employees. They've raised $20.7B in capital and serve 445.3M customers combined.
Sorting: Highest -> Lowest
Showing 10 of 135 companies ranked by annual revenue.
Lowell, Massachusetts, United States
RevBio, Inc., is a clinical stage medical device company developing and commercializing TETRANITE®, a patented, synthetic, injectable, self-setting, and osteoconductive bone adhesive biomaterial.
Billerica, Massachusetts, United States
Tenneo LMS is a robust learning platform that empowers learners & administrators equally. Depending on your learning needs, Tenneo offers four variants – Learn, Learn +, Grow & Act.
Cambridge, Massachusetts, United States
Radically simplifying digital media operations globally
Fall River, Massachusetts, United States
Gathering unstructured data is simple, but managing it effectively is more challenging. We simplify the unstructured data governance and management process into six steps to transform your files into Smart Data, ensuring their safety and reducing costs. Discover the only true end-to-end solution for your unstructured data with Congruity360.
Springfield, Massachusetts, United States
Perfecta is growing! www.perfecta.com/careers Join a mission-focused team where cutting edge ideas are welcomed and rewarded. Through innovative technology solutions and a deep understanding of what's at stake, our team ensures that the United States dominates the cybersecurity space. Continuous iteration and configuration allow our specific technology solutions to progress with confidence, collaboration, and efficiency. We invite all on our team to take pride in working on something essential that serves a greater purpose.
Boston, Massachusetts, United States
Indico Data's Decision Automation Platform powers insurance with real-time, actionable insights from unstructured data—fueling smarter risk assessment, sharper claims evaluation, and streamlined policy management.
Hingham, Massachusetts, United States
global provider of POS and store transformation solutions
Marlborough, Massachusetts, United States
Revinova specializes in helping B2B software & emerging technology companies increase revenue across the customer lifecycle. Our Knowledge-Led Growth™ approach sets us apart from the high-friction, salesy culture we’re changing. Why? → 61% of B2B customers prefer to be taught how to solve a problem rather than directly solving it for them. 💡 People like to be educated, they don’t like to be sold to. This philosophy drives us. We help clients increase new sales by meeting prospects with the educational content they seek. By developing more knowledgeable prospects and translating engagement data into actionable insights, Revinova challenges how B2B organizations traditionally market and sell their solutions.
Cambridge, Massachusetts, United States
GC Therapeutics (GCTx) uses synthetic biology to program patient-derived stem cells into various cell types in an efficient and scalable manner, aiming to revolutionize treatment across a broad range of therapeutic areas.
Boston, Massachusetts, United States
Purpose-built platform for data professionals and teams to learn skills, showcase projects and connect with experts
Each Tuesday, we reverse-engineer a real SaaS company's revenue, profit, CAC, funnels, and its top growth tactic.
Sign up to access all features
Sign up with GoogleSign up with LinkedInAlready have an account? Log in
GetLatka is trusted by 200k+ founders, researchers, and marketers.
No contracts, cancel at any time