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Top 843 SaaS Companies in Massachusetts, United States, May 2026

As of May 2026, there are 843 SaaS companies based in Massachusetts. They have combined revenues of $26.5B and employ 134.9K employees. They've raised $20.7B in capital and serve 445.3M customers combined.

Companies
843
Revenue
$26.5B
Funding
$20.7B
Employees
134.9K

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Top SaaS Companies in Massachusetts

Showing 10 of 160 companies ranked by annual revenue.

1
Torpedo Therapeutics

Boston, Massachusetts, United States

High-precision, closed-loop neuromodulation devices

Revenue
$1M
Customers
-
Year founded
2018
Funding
-
Team size
5
Growth
-
2
Brown Foods

Boston, Massachusetts, United States

Making 'REAL' Milk without any Cows!

Revenue
$1M
Customers
-
Year founded
2021
Funding
-
Team size
5
Growth
-
3
QuotaFactory

Framingham, Massachusetts, United States

The company primarily operates in the Software industry. QuotaFactory was founded in 2002 and is headquartered in Framingham, MA. Similar Companies include InsightSquared, Clari, and Tenfold (Computer Software) among others.

Revenue
$1M
Customers
-
Year founded
2002
Funding
-
Team size
3
Growth
147.94%
4
Helix Nanotechnologies

Boston, Massachusetts, United States

Next-generation mRNA platform to solve cancer, COVID and climate.

Revenue
$1M
Customers
-
Year founded
-
Funding
-
Team size
16
Growth
-
5
Promakhos Therapeutics

Boston, Massachusetts, United States

A therapeutics platform for curing inflammatory disorders

Revenue
$1M
Customers
-
Year founded
2021
Funding
-
Team size
5
Growth
-
6
Crews & co.

Braintree, Massachusetts, United States

Management consulting firm providing a proprietary operating system to help businesses increase revenue, profitability and salable asset value

Revenue
$1M
Customers
-
Year founded
2013
Funding
-
Team size
-
Growth
-
7
PipelineIQ

Andover, Massachusetts, United States

Founded in 2006, PipelineIQ builds deep-dive profiles on large enterprise prospects. Our insights fuel ABM and strategic account programs for the world's most successful technology sales and marketing teams.

Revenue
$1M
Customers
-
Year founded
2006
Funding
-
Team size
5
Growth
-
8
NetCommissions

Wakefield, MA, United States

Few things drive corporate success more than the performance of your sales organization. NetCommissions™ helps companies improve sales force productivity by providing market leading on-line sales commission management solutions that ensure performance feedback to the sales organization is timely, accurate and relevant.

Revenue
$1M
Customers
-
Year founded
2003
Funding
-
Team size
5
Growth
-
9
BioDataStudio

Boston, Massachusetts, United States

Intelligence Simplified. Built on our BioTriad framework—Science, Stakeholders, and Strategy—BioDataStudio.com delivers clean, real‑time dashboards and bespoke reports that empower biopharma vendors, investors, and R&D leaders to: > Find the right companies and assets shaping tomorrow’s therapies > Assess their financial health, pipeline status, and decision‑maker networks > Connect with the partners and opportunities that move the best medicines to market With BioDataStudio, you get the intelligence you need—without the noise—so you can make smarter, faster decisions in an ever‑changing landscape.

Revenue
$1M
Customers
-
Year founded
2023
Funding
-
Team size
-
Growth
-
10
Spearhead Capital Partners

Boston, Massachusetts, United States

Spearhead Capital Partners sources and invests in real estate emerging managers and provides advisory and capital raising services to those entities. Our four person team is located in AsiaPacific, the US and Canada.

Revenue
$1M
Customers
-
Year founded
-
Funding
-
Team size
-
Growth
-