Top 21 Manufacturing Execution System Software Companies With $10M–$100M Revenue (October 2026)

Tampa, Florida, United States

We make purpose-built software for specialty manufacturing and distribution businesses that streamline complex processes, optimize operations visibility and throughput, and drive improved quality, profitability, and revenue growth. Deeply embedded in our customers’ businesses, Advantive’s software solutions add value along the full manufacturing and distribution lifecycle. Our customers, who include corrugated and packaging manufacturers, equipment and supply wholesale distributors, and automotive and other specialty manufacturers, benefit from our solutions that have been honed over decades in the marketplace. We know our customers’ businesses intimately and deliver software to address their needs. Our software is deeply embedded in our customers’ operations. From schedule optimization and quality to sales order, inventory, and fulfillment management, from financial management to e-commerce to reporting and analytics, our software is designed to optimize every aspect of the manufacturing and distribution value chain. Specialized, scalable, and easy to use, our software optimizes performance and drives rapid value and ROI for our customers.

Irvine, California, United States

BatchMaster Software has helped process manufacturers worldwide streamline.

Somerville, Massachusetts, United States

Tulip, a leader in frontline operations, is helping companies around the world equip their workforce with AI-enabled, connected apps — leading to higher quality work, improved efficiency, and end-to-end traceability across operations. Tulip's composable platform enables those closest to operations can take advantage of composability and edge connectivity to digitally transform processes, guide operators, track production, and gain a real-time, holistic view of operations. Companies of all sizes and across industries — including complex manufacturing, pharmaceuticals, and medical devices — have implemented composable solutions with Tulip’s platform to solve some of the most pressing challenges in operations: error-proofing processes and boosting productivity with guided workflows, capturing and analyzing real-time data, and continuously improving operations. A spinoff out of MIT, the company is headquartered in Somerville, MA, with offices in Germany and Hungary. Interested in helping Tulip transform the manufacturing software landscape? We’re hiring! Browse our open roles and apply today: https://tulip.co/careers/.

Jacksonville, Florida, United States

At Revalize we empower manufacturing businesses to better design, model, develop and sell – driving greater outcomes across the entire value chain. No matter how volatile the landscape, Revalize provides a more efficient route from idea to cash. Our best-in-class CAD, PLM, and CPQ solutions – underpinned by a global support team – give you a single partner for increasing speed-to-market, reducing cost, and streamlining complexity. Wherever your business journey starts, greater outcomes start with Revalize.

Paris, France

Start-up studio specialised in Saas solutions for manufacturing issues

Noida, Uttar Pradesh, India

DesignX specializes in migrating and bridging manufacturing companies to Industry 4.0, offering functionalities including production audit and management, quality checks, safety audits, maintenance management, and supply chain management.

Quebec, Quebec, Canada

Poka transforms manufacturing operations by empowering workers with real-time access to knowledge, digital tools and expert support. Our AI-driven platform integrates training, communication and troubleshooting to foster continuous improvement and operational excellence. Our mission is to bridge the skills gap, reduce downtime, and drive safety, performance and quality to new heights. Poka’s powerful analytics engine makes it easy to identify issues in production, leading to quick and focussed resolutions. In 2023, Poka was acquired by IFS, an enterprise software leader in Enterprise Asset Management, Field Service Management and ERP. Together, we help manufacturing companies optimize their people, assets and processes. Join us in shaping the future of work in manufacturing.

Madrid, Spain

Provider of information technology services, serving as a technology partner for data-driven management for industrial SMEs in Spain. Their solutions include ERP, MES, Product Lifecycle Management, and Engineering services.

Frankfurt, Germany

Operations1 provides a solution for intuitive worker guidance and connects the organization in manufacturing companies.

Clinton Township, Michigan, United States

Godlan is a leading professional manufacturing services company that has been implementing integrated technology solutions since 1984. Godlan has successfully implemented thousands of enterprise manufacturing systems and performed countless data conversions. We have deep domain expertise and knowledge of best practices working with customers worldwide. Godlan consultants know the manufacturing industry, understand the challenges, and have first-hand experience with solving complex performance problems. Results…. On Time and On Budget. www.godlan.com Godlan is an Infor Gold Partner and Alliance Partner Multiple Infor Partner of the Year Infor Circle of Excellence Inc 5000 Fastest Growing Private Companies Inc Power Partner