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Top 7 Patient Engagement Software Companies $100M+ Revenue (August 2026)

As of August 2026, Latka tracks 7 patient engagement software companies with $100M+ in annual revenue. They have combined revenues of $2.1B and employ 3.4K people. They have raised $1.2B and serve 50K customers combined.

Every company below sells patient engagement software to other businesses and is ranked by its most recent annual revenue. Revenue, funding, headcount and customer figures come from CEO interviews on the Latka podcast, public company filings, and Latka estimates where a company has not disclosed a number.

What Patient Engagement Software Companies do

Patient engagement software encompasses a range of digital tools designed to improve communication and interaction between healthcare providers and patients. These solutions facilitate the management of various healthcare-related tasks, such as appointment scheduling, access to medical records, and medication tracking, empowering patients to take a more active role in their healthcare journeys. Moreover, they often provide educational resources and personalized communication to enhance the patient experience. Typical features of patient engagement software include secure messaging, appointment reminders, telehealth capabilities, and access to test results. The primary use cases focus on improving patient adherence to treatment plans, enhancing patient satisfaction, and fostering a collaborative relationship between patients and providers. These solutions are primarily utilized by healthcare organizations, including hospitals, clinics, and practice management groups, with key buyer personas often comprising healthcare administrators, practice managers, and IT professionals overseeing patient experience initiatives.

Companies
7
Revenue
$2.1B
Funding
$1.2B
Employees
3.4K

Filters

Sorting: Highest -> Lowest

Filters

Top Patient Engagement Software Companies $100M+ Revenue

Showing 7 of 7 companies ranked by annual revenue.

1HealthMark Group logo
HealthMark Group

dallas, Texas, United States

A software-driven provider of health information management solutions, pioneering an efficient, compliant and patient-centric approach

Revenue
$1B
Year founded
2006
Team size
446
2Monogram Health logo
Monogram Health

Brentwood, Tennessee, United States

Monogram Health is a leading multispecialty provider of in-home, evidence-based care and benefit management services for the most complex patients with multiple chronic conditions.

Revenue
$286.1M
Team size
767
3ekincare logo
ekincare

Hyderabad, Andhra Pradesh, India

Developer of a cloud-based medical networking platform designed to offer recommendations on healthcare interventions. The company's cloud-based medical networking platform monitors and gathers updated medical results from various healthcare service providers and helps in identifying potential health updates and risk as well as to take necessary steps towards improving health, enabling users to monitor their critical medical information and view it anywhere anytime.

Revenue
$252.5M
Customers
50K
Year founded
2014
Funding
$20.7M
Team size
204
4Perspectum Ltd logo
Perspectum Ltd

Oxford, England, United Kingdom

Perspectum is an innovative company in the field of precision health technology delivering advanced solutions to health care providers. Their cutting-edge digital technologies help clinicians provide better care for patients with liver disease, diabetes, and cancer.

Revenue
$162.8M
Year founded
2012
Team size
279
5Medlinker logo
Medlinker

Chengdu, China

Medlinker is a social networking platform connecting doctors, healthcare institutions, pharmaceutical companies, patients, and insurance firms. It focuses on disease prevention, diagnosis, treatment, and rehabilitation, and is a prominent player in China's internet healthcare sector.

Revenue
$150M
Funding
$836.3M
Team size
1K
6Virtix Health logo
Virtix Health

Phoenix, Arizona, United States

Virtix Health partners with health plans across the country to drive clinical, financial, and operational results. They offer virtual wellness visits, in-home health risk assessments, retrospective chart review, workflow technology and member/patient engagement.

Revenue
$110.7M
Year founded
2018
Team size
217
7EliseAI logo
EliseAI

United States

EliseAI empowers housing and healthcare organizations with powerful automation and conversational AI, streamlining conversations, enhancing customer engagement, and delivering unparalleled efficiency across housing and property management operations.

Revenue
$100M
Year founded
2017
Funding
$325M
Team size
453

Frequently asked questions about Patient Engagement Software Companies $100M+ Revenue

How many patient engagement software companies with $100M+ in annual revenue are there?

Latka tracks 7 patient engagement software companies with $100M+ in annual revenue. Together they generate $2.1B in annual revenue and employ 3.4K people.

Which patient engagement software company with $100M+ in annual revenue is the largest?

HealthMark Group is the largest, with $1B in annual revenue, founded in 2006.

How much revenue does a typical patient engagement software company with $100M+ in annual revenue make?

The average patient engagement software company in this list makes $294.6M a year, across 7 companies with reported revenue. They serve 50K customers combined.

Who are the leading Patient Engagement software vendors with $100M+ in annual revenue?

Ranked by annual revenue, the leaders are HealthMark Group, Monogram Health, ekincare, Perspectum Ltd and Medlinker.

How much funding have patient engagement software companies with $100M+ in annual revenue raised?

The 7 patient engagement software companies with $100M+ in annual revenue tracked here have raised $1.2B in disclosed funding between them.

Related Vertical Industry Software categories

Inclusion Criteria

- Must enable two-way communication between patients and healthcare providers. - Should provide tools for self-management, such as appointment scheduling and access to medical information. - Must include educational resources to inform patients about their conditions and treatments. - Should support remote consultations through telehealth functionalities. - Not just limited to patient data storage; must also facilitate engagement and interaction. - Must comply with healthcare data security and privacy regulations.