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Top 487 SaaS Companies in Palo Alto, United States, May 2026

As of May 2026, there are 487 SaaS companies based in Palo Alto. They have combined revenues of $8.5B and employ 44.5K employees. They've raised $16.4B in capital and serve 23.3M customers combined.

Companies
487
Revenue
$8.5B
Funding
$16.4B
Employees
44.5K

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Top SaaS Companies in Palo Alto

Showing 10 of 158 companies ranked by annual revenue.

1
Intact Therapeutics

Palo Alto, California, United States

Smart gels for local drug delivery to the gut

Revenue
$1M
Customers
-
Year founded
2015
Funding
-
Team size
5
Growth
-
2
Feenix.ai

Palo Alto, California, United States

Accelerate Your Multi-Cloud Marketplace Journey & Grow Your Business List your SaaS solution on any cloud marketplace, in less than 15-minutes

Revenue
$1M
Customers
-
Year founded
-
Funding
-
Team size
11
Growth
-
3
Tappity

Palo Alto, California, United States

World's largest library of interactive lessons for kids

Revenue
$1M
Customers
-
Year founded
2018
Funding
-
Team size
13
Growth
-
4
VipeCloud

Palo Alto, California, United States

The #1 Rated CRM For Usability And Customer Satisfaction, Vipecloud Is A Complete Sales CRM And Marketing Suite With Unparalleled Support. Get Started Free!

Revenue
$1M
Customers
-
Year founded
2011
Funding
-
Team size
6
Growth
-
5
Recruiter.AI

Palo Alto, California, United States

Recruiter.ai is on a mission to provide life changing opportunities to talented people by making recruiting smart, fair, and efficient. Using the power of artificial intelligence, we predict the next best role for candidates and help companies discover great employees. By removing all bounds that stifle employment possibilities, we help people and businesses grow.

Revenue
$1M
Customers
-
Year founded
2015
Funding
-
Team size
11
Growth
-
6
Superbio.ai

Palo Alto, California, United States

AI marketplace for life sciences

Revenue
$1M
Customers
-
Year founded
2021
Funding
-
Team size
9
Growth
-
7
Rejoy Health

Palo Alto, California, United States

AI tools and LLM for Healthcare

Revenue
$1M
Customers
-
Year founded
2021
Funding
-
Team size
6
Growth
-
8
Helpwise

Palo Alto, California, United States

Helpwise is an easy-to-use customer service platform that allows teams to answer all customer queries across multiple channels from one single place in less time.

Revenue
$1M
Customers
10K
Year founded
2019
Funding
-
Team size
8
Growth
-
9
OWNY

Palo Alto, California, United States

Manage capital, investors & banking in one place.

Revenue
$1M
Customers
-
Year founded
2019
Funding
-
Team size
6
Growth
-
10
Rypple.ai

Palo Alto, California, United States

Never Lead Alone with Rypple.ai Rypple is reimagining leadership for the modern world. We built an AI leadership team to help managers lead smarter — across every major area of management accountability. More than coaching — Rypple is built to help you get things done. Run smarter meetings. Handle tough conversations. Delegate effectively. Lead with confidence. Spend less time managing chaos, and more time making an impact. What makes Rypple different? ✅ Six specialized AI assistants — covering people, performance, communication, operations, strategy, and self-leadership ✅ MeetingHQ Intelligence — turns every meeting into a progress engine with AI prep, live insights, and automated follow-ups ✅ Smart Boosters & Automations — free you from repetitive prep and admin with intelligent workflows ✅ 24/7 voice-to-voice coaching and support — talk through challenges, reflections, and decisions anytime, anywhere ✅ Trusted by 15,000+ managers at leading tech companies and organizations worldwide ✅ SOC 2 Type I certified — built on trust, security, and privacy For Managers: Save time, grow your capacity, and lead with confidence. 👉 Get started today: www.rypple.ai #NeverLeadAlone

Revenue
$990K
Customers
-
Year founded
2024
Funding
$7M
Team size
9
Growth
-