Top 16 SaaS Companies in South San Francisco, United States, May 2026

South San Francisco, California, United States

an online payments company that provides businesses with a platform to accept payments online.

South San Francisco, California, United States

Glydways, formerly Wayfarer, is a transportation technology and clean energy company based in South San Francisco, California. It specializes in the design, manufacture, installation, and operation of affordable autonomous transportation for low, medium, and extremely high-capacity needs.

South San Francisco, California, United States

ProcDNA is a consulting firm specializing in commercial analytics and technology, primarily serving the life sciences sector. They create game-changing Commercial Analytics and Technology solutions.

South San Francisco, California, United States

Cellares is the first Integrated Development and Manufacturing Organization (IDMO) that develops and operates integrated technologies for cell therapy manufacturing, aiming to accelerate access to life-saving cell therapies.

South San Francisco, California, United States

Simbe Robotics builds automation solutions for shelf auditing and analytics. The company provides out of stock management, pricing and promo execution, planogram compliance, inventory tracking, and remote compliance solutions, specifically in the retail sector using advanced computer vision and AI-powered automation.

South San Francisco, California, United States

Claritas Rx helps rare disease and specialty brands remove the barriers that keep patients from accessing and staying on the treatments they need. By uniting the most complete view of the patient journey with purpose-built technologies, we predict and resolve access challenges before they disrupt care. Our intelligent solutions combine advanced analytics, real-world data, AI, and in-line CRM capabilities to increase start and refill rates, reduce abandonment, and improve brand performance. For more information, visit www.ClaritasRx.com.

South San Francisco, California, United States

At Bright Pattern, we're paving the way for the future of contact center technology. We offer an all-in-one solution that brings ease, efficiency, and personalization to customer service interactions. What sets us apart is our omnichannel capabilities. Our enterprise-grade contact center platform provides agents an omnichannel desktop to handle all interactions on every channel in one screen – “a single pane of glass”. With prior customer journey history readily available, agents can quickly switch between channels and communicate with customers in a natural way tailored to their needs. This reduces effort for both customers and agents, allowing for personalized conversations. Trusted by 500 customers in 26 countries, we are the highest-rated omnichannel platform by customers and analysts with the fastest ROI and time to deploy in the industry. OMNICHANNEL CONVERSATIONS Easy, seamless omnichannel conversation across voice and digital channels for both customers and agents. OMNICHANNEL QUALITY MANAGEMENT Monitor 100% of interactions on every channel and allow you to review, score and coach agents to improve CX. OMNI-ENTERPRISE CX™ Allow any employee to connect on voice and digital channels via Bright Pattern Mobile App.

South San Francisco, California, United States

Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders, developing a novel platform to treat cancer.

South San Francisco, California, United States

At BrightestMinds, we're incubating the Sales Development Reps of the future, supercharged with intent-driven data and tools under one solution. We've achieved 10x cost efficiency vs AdWords. We had cases when clients requested that we slow down, as they were unable to process so many leads. We work with tech startups and unicorns. Many of our clients doubled, tripled and quadrupled the number of SDRs assigned to help them with lead generation. Since 2017, we grew from one to a globally distributed team of over 50 high-performing, happy people that are dedicated to innovating and creating new ways to exceed in lead generation. Talk to us now; schedule a call via https://calendly.com/bmteam

South San Francisco, California, United States

Medical device that provides a more effective, less invasive…