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Top 16 SaaS Companies in South San Francisco, United States, May 2026

As of May 2026, there are 16 SaaS companies based in South San Francisco. They have combined revenues of $19.7B and employ 11.5K employees. They've raised $9.4B in capital and serve 1M customers combined.

Companies
16
Revenue
$19.7B
Funding
$9.4B
Employees
11.5K

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Top SaaS Companies in South San Francisco

Showing 10 of 6 companies ranked by annual revenue.

1
Zenflow

South San Francisco, California, United States

Medical device that provides a more effective, less invasive…

Revenue
$5M
Customers
-
Year founded
2014
Funding
-
Team size
29
Growth
-
2
Noetik

South San Francisco, California, United States

Noetik is an AI-native biotechnology company that leverages advanced machine learning methods to discover and develop cancer immunotherapies.

Revenue
$3.9M
Customers
-
Year founded
2022
Funding
-
Team size
42
Growth
-
3
Faction

South San Francisco, California, United States

Driverless electric vehicles at a fraction of the cost of a car.

Revenue
$3.3M
Customers
-
Year founded
2020
Funding
-
Team size
22
Growth
-
4
Selly Automotive CRM

South San Francisco, California, United States

Developer of a full CRM & ILM (Internet Lead Management) platform intended to allow dealers to manage internet leads and customer follow-ups. The company's platform is priced affordable for even the smallest used car dealer, and integrates with many of the solutions users already use as well as their DMS system.

Revenue
$2.7M
Customers
-
Year founded
2014
Funding
$655K
Team size
19
Growth
92.57%
5
Vivum AI

South San Francisco, California, United States

We are not a conventional artificial intelligence company. Vivum pioneers Evolutionary AI (E-AI) through a cutting-edge platform that harnesses the power of biological intelligence. By leveraging dynamic learning models like liquid time-constant networks, we deploy adaptive, energy-efficient E-AI models to edge devices without costly supercluster CPUs/GPUs. Vivum’s transparent, context-aware models empower autonomous vehicles, advanced robotics, and intelligent devices to navigate, perform, and decide in complex, real-time scenarios. We’re committed to forging a biospheric computing paradigm that benefits not just humanity but all life on Earth. The planet demands it.

Revenue
$1.9M
Customers
-
Year founded
2023
Funding
-
Team size
17
Growth
-
6
Nectome

South San Francisco, California, United States

Building a way to preserve long-term memories.

Revenue
$1M
Customers
-
Year founded
-
Funding
-
Team size
5
Growth
-
South San Francisco, United States SaaS Companies | GetLatka