Top 13 E-Prescribing Software Companies (August 2026)

Los Angeles, California, United States

MDI Health is a Tel Aviv-based health technology company founded in 2019 that has built an AI-powered platform to optimize medication treatments for health payers and providers, including large health systems and health insurance companies. The company targets what it describes as the fourth leading cause of death in the United States: problems stemming from medications. Its software analyzes patient medication regimens, identifies risks such as dangerous drug interactions, and recommends clinical interventions to reduce adverse outcomes. As of late 2021, MDI Health had approximately six enterprise customers, each representing contract value potential in the millions of dollars, with one health system customer operating roughly 90 hospitals. The company closed an $8 million seed round around the end of 2020 and carried a team of 25 employees. Revenue figures were not disclosed publicly by the company. MDI Health was planning to raise a Series A within 12 months of the interview, citing strong inbound interest from funds and a pipeline that, according to Ariel Efergan, the company's Global Vice President of Growth, exceeded its current capacity to serve.

Mount Laurel, New Jersey, United States

Nuvem integrates comprehensive and compliant pharmacy solutions with clinical care to increase access to affordable drugs, improve patient outcomes, and optimize financial results for healthcare providers.

Columbus, Ohio, United States

GiftHealth is a healthcare tech startup that streamlines pharmacy experience with free delivery and competitive medication pricing, enhancing the Rx experience for manufacturers, providers, and patients.

Bordeaux, Nouvelle-Aquitaine, France

At Synapse Medicine, we believe in medication success, and are dedicated to creating the technology that makes it possible for everyone. To achieve this goal, we have built an extensive global knowledge base for medication using algorithms to ensure the most reliable, up-to-date data. On the front-end, Synapse Medicine provides a SaaS platform and UI components that are used to prescribe, dispense, and manage medications across the entire patient journey. Synapse is working with world-leading hospitals and digital health companies in the United States, Europe, and Japan to transform today’s medication regimens into tomorrow’s medication success.

Cambridge, Cambridgeshire, United Kingdom

Healthera is a digital health platform that provides patients with medicines, healthcare services, and products through the largest digital healthcare marketplace. Founded in 2015 in the United Kingdom, it consists of a patient-facing app, a patient-facing website, and a pharmacy-facing platform.

Karachi, Pakistan

Operator of an online retail pharmacy platform. The company provides home delivery of genuine medicines, personal care products and authentic health products. It also provides online health counseling and advice.

Dover, Delaware, United States

DecisionRx is a technology-enabled healthcare services company that helps prescribers optimize medication therapy, improving patient outcomes and reducing healthcare costs.

Vancouver, British Columbia, Canada

GenXys provides the world's most comprehensive precision prescribing software to solve healthcare's most pressing challenges. Our precision prescribing software and pharmacogenetic solutions prevent adverse drug reactions, the 4th leading cause of death in the US, and personalize drug selection to increase drug efficacy. Powering every prescription with our software improves medication safety, increases drug efficacy and reduces healthcare costs. Our expert team is leading the way in precision prescribing with a cutting-edge technology that has dramatically changed the lives of our customers. We work diligently with patients and healthcare providers to personalize medication options and help them find the right medication right from the start. We offer precision prescribing software and pharmacogenetic testing to HMOs, ACOs and employers looking to integrate personalized medicine into their benefits plans and license our technology to clinical laboratories.

Poznań, Wielkopolska, Poland

Mediporta is a software company that provides electronic medical documentation (EDM), e-referrals, e-prescription services, and commercial services primarily for healthcare facilities.

Gothenburg, Vastra Gotaland, Sweden

Provider of a healthcare platform designed to offer intelligent services to increase the quality of medical treatments. The company's healthcare platform offers services to increase patient support and addresses the problem of poor adherence to prescription instructions, providing the healthcare industry and patients with reminders via automated phone calls, sms or push notifications in regards to which pill has been taken in real-time.