Top 28 Endpoint Protection Software SaaS Companies in May 2026

Boston, Massachusetts, United States

Lookout is a cybersecurity company that provides cloud-based mobile security solutions for individuals and enterprises. The company's software protects mobile devices from various threats, including malware, phishing, and data breaches, and offers additional features such as identity protection and device management. Lookout was founded in 2007 and is headquartered in San Francisco, California. The company serves customers in various industries, including financial services, healthcare, and government, among others.

Orlando, Florida, United States

The ThreatLocker® story. ThreatLocker journey began with a mission to protect businesses from the devastating effects of cyberattacks. Co-founders Danny Jenkins, Sami Jenkins, and John Carolan set out to create solutions designed to eliminate the guessing game of cybersecurity. Danny Jenkins began his cybersecurity career in 1997, which included roles such as managing corporate IT, ethical hacking, and becoming an entrepreneur. A significant turning point occurred when Jenkins witnessed the aftermath of a severe phishing attack. The attack disrupted business operations and nearly resulted in the loss of the company. This incident underscored the critical gaps in existing reactive cybersecurity strategies and motivated Jenkins to develop a proactive, Zero Trust solution designed to give businesses more control over their defenses. With this commitment, along with Sami Jenkins and John Carolan, he co-founded ThreatLocker, making the Zero Trust approach to cybersecurity reality for many. In just a few years, over 50,000 businesses worldwide have embraced ThreatLocker solutions, a testament companies are ready to move beyond the endless game of trying to outsmart cybercriminals and are adopting instead new, proactive ways to defend against them with ThreatLocker redefining Zero Trust solutions.

Dallas, Texas, United States

Developer of security systems designed to protect company from device, network and application-based attacks. The company's security systems offers real-time, on-device protection against both known and unknown Android and iOS threats, enabling enterprises of all sizes, large federal and local government agencies, leading mobile operators and major OEM partners to protect mobile data, applications and sessions against device compromises, network attacks and malicious applications.

Broomfield, Colorado, United States

Webroot, an OpenText company, was the first to harness the cloud and artificial intelligence to stop zero-day threats in real time. We provide endpoint protection, network protection, and security awareness training solutions purpose built for managed service providers and small businesses. Webroot BrightCloud® Threat Intelligence Services are used by market leading companies like Cisco, F5 Networks, Citrix, Aruba, A10 Networks, and more. Leveraging the power of machine learning to protect millions of businesses and individuals, Webroot secures the connected world. In 2019, Webroot and its parent company Carbonite were acquired by OpenText, a global leader in Enterprise Information Management. Together, we are a market leader in cyber resilience, offering total endpoint protection and disaster recovery for any sized business. Discover endpoint security and disaster recovery solutions at webroot.com. In 2019, Webroot was acquired by Carbonite, an endpoint and server backup and recovery provider serving customers ranging from small businesses to enterprises. Together, we are a leading cybersecurity and data protection company.

Naples, Florida, United States

Managed security service provider protecting endpoints, networks, applications, cloud and data from threats, risks, attacks and more.

London, England, United Kingdom

Developer of anti-malware products designed to revolutionize enterprise cyber-security. The company's anti-malware products offer highly effective fundamental security challenges for enterprise and cloud computing, enabling its users to access all content on the web without any risk of exposing their organization to cyber-attack.

Boston, Massachussetts, Israel

Developer of a cyber threat prevention software designed to reinvent end-point security. The company's threat prevention software exploits advanced threat tactics like deception, modification and polymorphism to conceal vulnerabilities in applications, web browsers and OS's and traps any attempts at access, turning the end-points into a line of defense, enabling companies to neutralize attacks at the moment they happen, no matter what form they take.

Santa Clara, California, United States

Malwarebytes is a cybersecurity company that provides software solutions to protect against malware, viruses, and other online threats. The company's flagship product is Malwarebytes Anti-Malware, which uses advanced technology to detect and remove malicious software from computers and mobile devices. Malwarebytes also offers a range of other cybersecurity products and services, including endpoint protection, threat intelligence, and incident response. The company was founded in 2008 and is headquartered in Santa Clara, California.

Nashua, New Hampshire, United States

Developer of a security software designed to simplify enterprise access control. The company's software closes security gaps and ensures only trusted, known assets connect to corporate networks and provides real-time defense against cyber attacks including zero-days, phishing and ransomware, enabling IT professionals to regain control of their networks and enhance organizations cyber-risk mitigation strategies.

Minneapolis, Minnesota, United States

CrashPlan provides peace of mind through secure, scalable, and straightforward endpoint data backup. We help organizations recover from any worst-case scenario, whether it is a disaster, simple human error, a stolen laptop, ransomware or an as-of-yet undiscovered calamity. We continue to innovate as the landscape of work evolves, which makes CrashPlan foundational to organizations’ data security. What starts as endpoint backup and recovery becomes a solution for ransomware recovery, breaches, migrations, and legal holds. CrashPlan protects more than 50,000 world-class organizations, including the largest global brands. While having existed as a product for more than a decade, in 2022, CrashPlan separated from our previous corporate parent to exclusively focus on backup and recovery. The company is headquartered in Minneapolis, Minnesota.