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Top 24 Healthcare Integration Engines SaaS Companies in May 2026

As of May 2026, there are 24 SaaS companies in Healthcare Integration Engines. They have combined revenues of $464M and employ 2.2K people. They have raised $428.8M and serve 40M customers combined.

Healthcare Integration Engines are specialized software solutions designed to facilitate the seamless exchange, integration, and management of healthcare data across various systems and platforms. They serve critical functions in enhancing interoperability among diverse healthcare applications, enabling secure communication, data sharing, and efficient processing. These engines play a vital role in ensuring that different healthcare IT systems, such as Electronic Health Records (EHRs) and laboratory information systems, can communicate effectively, ultimately improving patient care and operational efficiency. Use cases for Healthcare Integration Engines include the integration of billing and scheduling systems, clinical decision support, and the processing of health data from multiple sources. Typical features of these engines may include support for health data standards (e.g., HL7, FHIR), data transformation, real-time monitoring, and user-friendly interfaces for configuration. Common buyer personas for these solutions often include IT professionals within healthcare organizations, data analysts, and clinical operations managers who need to ensure that key health information flows smoothly across systems while maintaining compliance with regulatory requirements.

Companies
24
Revenue
$464M
Funding
$428.8M
Employees
2.2K

Filters

Sorting: Highest -> Lowest

Filters

Top Healthcare Integration Engines Companies

Showing 10 of 6 companies ranked by annual revenue.

1
tack

United States

tack is an IT consulting company in the San Francisco Bay Area focused on CRM and EHR, and professional services generally. We help professionals get things done faster and better by focusing on the systems that provide the greatest payoff in productivity and revenue. We can help you choose a new application, integrate it with existing data, and even get the paperwork in to claim meaningful use.

Revenue
$550K
Customers
-
Year founded
2008
Funding
-
Team size
5
Growth
-
2
XchangeLabs

Richardson, Texas, United States

In 2012, the founders of XchangeLabs saw an opportunity to provide a cloud-based solution for sharing large volumes of confidential health care information that would enhance not only the quality of care being provided but speed the delivery of health care to patients throughout the continuum of care. As their vision for affordable and safe health care for everyone grew they founded XchangeLabs with the ambitious mandate of delivering affordable, secure and fully integrated health care systems with a service experience second to none. Today, our product suites are capable of integrating with many existing systems available on the market, across many healthcare verticals and are capable of processing millions of transactions per day.

Revenue
$440K
Customers
-
Year founded
2012
Funding
-
Team size
4
Growth
-
3
HealthBlocks

United States

Founded in 1999, HealthBlocks began with a vision of creating a web portal for healthcare. While the vision was never realized, the process led us to our true calling: middleware for device connectivity and integration. Since our flagship product's first production version in 2004, we have solved and continue to solve complex integration problems where other solutions have failed. ENQ connects devices, instruments, and systems together, and provides an advanced toolkit for integrating all connected components into your organization's workflow in a seamless manner.

Revenue
$220K
Customers
-
Year founded
1999
Funding
-
Team size
2
Growth
-
4
Kaelio

San Francisco, California, United States

AI operating system for healthcare organizations

Revenue
$220K
Customers
-
Year founded
2025
Funding
-
Team size
2
Growth
-
5
BestConsent

Melbourne, Florida, United States

Developer of a software application designed to remain cost-effective through using open source technologies such as MySQL, Mirth and Linux. The company's software application provides medical records starter kits, B-forms, eForms data capture, medical and document imaging, clinical multimedia and integration engines, registration and convenience scanning and document conversion tools, enabling small hospitals, large hospital systems and public healthcare to meet their customized workflow need.

Revenue
$132.3K
Customers
-
Year founded
1993
Funding
-
Team size
1
Growth
26.5%
6
Collaborative Medical Technology

Paramus, New Jersey, United States

Provider of a cloud-based platform for cross-enterprise connectivity among healthcare professionals. The company provides telehealth and mobile health services for hospitals, physicians, specialist, providers, patients/caregivers and payers.

Revenue
$99.8K
Customers
-
Year founded
1999
Funding
-
Team size
1
Growth
26.5%

Inclusion Criteria

- Must facilitate data integration and interoperability between multiple healthcare systems - Should support industry-standard protocols such as HL7 and FHIR - Must enable real-time data processing and communication - Should include data transformation and mapping capabilities - Must offer robust user interfaces for system configuration and monitoring - Not just for data storage; must also ensure data accessibility and flow across platforms