Top 101 SaaS Companies in Cambridge, United States, May 2026

Cambridge, Massachusetts, United States

Radically simplifying digital media operations globally

Cambridge, Massachusetts, United States

GC Therapeutics (GCTx) uses synthetic biology to program patient-derived stem cells into various cell types in an efficient and scalable manner, aiming to revolutionize treatment across a broad range of therapeutic areas.

Cambridge, Massachusetts, United States

uConnect built the first all-in-one virtual career center platform designed to radically improve student engagement. Our mission is to empower the next generation to realize their full potential by improving access to career resources, networks, and opportunities—early in their lives and throughout their careers. Over 90% of students enrolling in college indicated that employment was their primary or sole motivation, yet half of U.S. college students graduate without ever having used career services or its online resources. uConnect's virtual career center combines career content management and modern student communication to improve visibility, accessibility, and utilization of high-impact career services for students, faculty, and the campus community. Schools like MIT, Arizona State, Yale, University of Florida, and UCLA use uConnect to elevate the role of career services to a strategic competitive advantage to inspire purposeful pathways from education to employment. Developed directly from the experience of our founder, uConnect is deeply committed to ensuring every young person can access the career information and support they need to succeed, regardless of their age, what school they go to, or where they are from. uConnect is backed by leading education technology investors, including Strada Education, LearnLaunch, and Growth Street Partners.

Cambridge, Massachusetts, United States

Labguru, the flagship product of BioData, recently acquired by Battery Ventures, is a trusted provider serving more than 750 global customers, including national research institutes, academia, global pharma, and innovative startups worldwide. Scientists utilize Labguru to plan, document, track, streamline, automate, and share their research and production. Labguru is a secure, cloud-based data management platform offering a comprehensive solution for life science research and industry. It encompasses an Electronic Lab Notebook (ELN), LIMS, and an informatics platform, along with molecular biology and chemistry tools to facilitate lab automation. Customizable experiment templates, protocol integration, SOPs, and other advanced features enhance data quality, streamline workflows, and reduce costs. Labguru is accessible on desktops and mobile devices via the cloud. For more information, visit www.labguru.com.

Cambridge, Massachusetts, United States

TileDB is foundational software designed by scientists for scientific discovery. TileDB structures all data types, including that data that does not fit into relational databases built for structured tabular data. Built on a powerful shape-shifting array database, TileDB handles the complexities of non-traditional “unstructured” multimodal data, such as genomic variants, bulk and single-cell transcriptomics, proteomics, biomedical imaging, as well as the frontier data of the future. Used by science and data teams within big pharma and biotechs to power their multiomic FAIR data platforms, TileDB is the destination for scientific breakthroughs where frontier multimodal data is driving drug discovery.

Cambridge, Massachusetts, United States

Elemental Machines’ Intelligent Operations Platform leverages the best of Internet of Things (IoT) technology and custom hardware/software solutions, delivering actionable insights to operators in life sciences, biopharma labs, biobanks, analytical labs, and manufacturing facilities. By connecting the physical and digital worlds, the platform simplifies, optimizes, and augments operations. Leaders in science, facilities, and technology trust Elemental Machines’ ecosystem for insights that accelerate innovation, predict outcomes, and shift from reactive to proactive management. With scalable solutions from incubator to enterprise, custom integrations to fit each operation’s unique needs, and a wide ecosystem of partnerships, Elemental Machines ensures operational excellence and the future-proofing of lab and manufacturing processes.

Cambridge, Massachusetts, United States

Collaborate with colleagues, share & markup design assets, & build interactive presentations with Modelo, a centralized communication hub for architects & designers.

Cambridge, Massachusetts, United States

Developer of open-source language software designed to make programming language easy to deploy, use and scale. The company's open-source language software is used for data science, machine learning and scientific computing which includes research, back testing, trading, contract modeling and series analytics as well as provides the functionality, ease-of-use and intuitive syntax of R, Python, Matlab, SAS or Stata combined with the speed, capacity and performance of C, C++ or Java, enabling users to receive a fast and modern language for crunching data.

Cambridge, Massachusetts, United States

Unlocking the utility of genomics for the world.

Cambridge, Massachusetts, United States

Mantel is a pioneering startup specializing in advanced materials designed for high-temperature carbon capture. It is developing the first molten-salt based carbon capture technology that operates at high temperatures, aiming to significantly lower carbon capture costs across diverse sectors.