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Top 404 SaaS Companies in Chicago, United States, May 2026

As of May 2026, there are 404 SaaS companies based in Chicago. They have combined revenues of $10.2B and employ 60.1K employees. They've raised $6.2B in capital and serve 39.3M customers combined.

Companies
404
Revenue
$10.2B
Funding
$6.2B
Employees
60.1K

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Top SaaS Companies in Chicago

Showing 10 of 131 companies ranked by annual revenue.

1
Synapticure

Chicago, Illinois, United States

We deliver personalized medicine for neurodegenerative patients

Revenue
$5M
Customers
-
Year founded
2019
Funding
-
Team size
35
Growth
-
2
LearnQ Inc.

Chicago, Illinois, United States

The #1 AI Tool For Digital SAT Being Used By Lakhs Of Users & Educators From 139+ Countries. It Is A full-stack AI Platform For All The Digital SAT Prep Requirements.

Revenue
$5M
Customers
-
Year founded
-
Funding
-
Team size
16
Growth
-
3
JuraLaw

Chicago, Illinois, United States

JuraLaw is the first 100% web-based legal calendar management system.

Revenue
$5M
Customers
300K
Year founded
2012
Funding
-
Team size
3
Growth
1998.49%
4
Charge Running

Chicago, Illinois, United States

Provides live, virtual running classes to runners all around the world

Revenue
$5M
Customers
-
Year founded
2016
Funding
-
Team size
3
Growth
-
5
Softal Technologies

Chicago, Illinois, United States

Technology recruitment and consulting company helping clients build technology teams that drive innovation and create great software

Revenue
$5M
Customers
-
Year founded
2010
Funding
-
Team size
20
Growth
-
6
Amplify HR Management

Chicago, Illinois, United States

Firm providing comprehensive human resources solutions to small and midsize businesses, including payroll, tax administration and employee benefit programs

Revenue
$4.8M
Customers
-
Year founded
2017
Funding
-
Team size
44
Growth
-
7
Catsy

Chicago, Illinois, United States

Catalog Syndication >>> Shopify, BigCommerce, Amazon, and major distributors. Catsy’s Syndication Trifecta is engineered to keep your content on course. 1. Content Accuracy 2. Channel Compatibility 3. Automated Distribution With Catsy, you can drive digital growth by updating product content across your customer channels and providing secure branded portals for CSRs and Sales reps. Speak with our dedicated team. Book a demo at catsy.com.

Revenue
$4.7M
Customers
-
Year founded
2003
Funding
-
Team size
43
Growth
-
8
Bitnomial

Chicago, Illinois, United States

Bitnomial, Inc. is a derivatives exchange company that operates a U.S. CFTC-regulated exchange and a clearinghouse, specializing in digital asset futures and options trading. Founded in 2014, it aims to connect native digital asset hedgers with institutional traders through improved derivatives exchange technology and new settlement systems.

Revenue
$4.7M
Customers
-
Year founded
2014
Funding
-
Team size
26
Growth
-
9
OpenMarkets

Chicago, Illinois, United States

Provider of a technology-enabled healthcare service for purchasing capital equipment. The company provides a network of healthcare providers joined together to track equipment needs and then leverages the combined volume in order to negotiate better pricing with suppliers through an online marketplace.

Revenue
$4.7M
Customers
-
Year founded
2010
Funding
-
Team size
20
Growth
210.85%
10
ElectronX

Chicago, Illinois, United States

ElectronX is a U.S.-regulated energy exchange created to address volatile short-term price exposure to electricity. It provides financial infrastructure for the transition to renewable energy sources.

Revenue
$4.6M
Customers
-
Year founded
2022
Funding
-
Team size
38
Growth
-