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Top 19 SaaS Companies in Saint Louis, United States, July 2026

As of July 2026, there are 19 SaaS companies based in Saint Louis. They have combined revenues of $1.1B and employ 870 employees. They've raised $63.1M in capital and serve 519 customers combined.

Companies
19
Revenue
$1.1B
Funding
$63.1M
Employees
870

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Sorting: Highest -> Lowest

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Top SaaS Companies in Saint Louis

Showing 10 of 6 companies ranked by annual revenue.

1Netelligent Corporation logo
Netelligent Corporation

Saint Louis, Missouri, United States

Netelligent provides companies with the technologies they need to run their business (security, phone system, servers/virtualization)

Revenue
$88.9M
Customers
-
Year founded
2003
Funding
$25M
Team size
23
Growth
-
2TCARE logo
TCARE

Saint Louis, Missouri, United States

TCARE supports caregivers through the complexities of caregiving to help health plans, employers, and families get to a place of better care. It is a family caregiver support platform designed to prevent caregiver burnout and help keep care at home.

Revenue
$54.6M
Customers
-
Year founded
2014
Funding
-
Team size
97
Growth
-
3Coolfire logo
Coolfire

Saint Louis, Missouri, United States

real-time situational awareness software

Revenue
$16.5M
Customers
-
Year founded
2010
Funding
$20.6M
Team size
19
Growth
-
4Infoplus logo
Infoplus

Saint Louis, Missouri, United States

Infoplus is a powerful yet simple warehouse, inventory management, shipping software for e-Commerce and 3PL warehouses, retailers, distributors, and wholesalers.

Revenue
$15M
Customers
-
Year founded
2013
Funding
-
Team size
11
Growth
-
5Native Pet logo
Native Pet

Saint Louis, MO, United States

Native Pet is a pet food and nutrition company that makes organic, highly effective, and limited-ingredient pet supplements for dogs and cats.

Revenue
$13.4M
Customers
-
Year founded
2017
Funding
-
Team size
55
Growth
-
6US Cloud logo
US Cloud

Saint Louis, Missouri, United States

Provides reputable Microsoft enterprise support to clients world-wide. Enables Microsoft Premier (Unified) Support customers to enjoy ultra-responsive support from US citizens, saving 30-60% on support costs and freeing up funds to drive innovation

Revenue
$10M
Customers
-
Year founded
2006
Funding
-
Team size
124
Growth
-
Saint Louis, United States SaaS Companies | GetLatka