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Top 19 SaaS Companies in Saint Louis, United States, May 2026

As of May 2026, there are 19 SaaS companies based in Saint Louis. They have combined revenues of $1.1B and employ 870 employees. They've raised $63.1M in capital and serve 519 customers combined.

Companies
19
Revenue
$1.1B
Funding
$63.1M
Employees
870

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Top SaaS Companies in Saint Louis

Showing 10 of 19 companies ranked by annual revenue.

1
plug

SAINT LOUIS, Missouri, United States

Your go-to destination for certified, pre-owned tech, offering up to 70% off retail prices on iPhones, MacBooks and more

Revenue
$891.3M
Customers
-
Year founded
2017
Funding
-
Team size
17
Growth
-
2
Netelligent Corporation

Saint Louis, Missouri, United States

Netelligent provides companies with the technologies they need to run their business (security, phone system, servers/virtualization)

Revenue
$88.9M
Customers
-
Year founded
2003
Funding
$25M
Team size
23
Growth
2318.18%
3
TCARE

Saint Louis, Missouri, United States

TCARE supports caregivers through the complexities of caregiving to help health plans, employers, and families get to a place of better care. It is a family caregiver support platform designed to prevent caregiver burnout and help keep care at home.

Revenue
$54.6M
Customers
-
Year founded
2014
Funding
-
Team size
97
Growth
-
4
Coolfire

Saint Louis, Missouri, United States

real-time situational awareness software

Revenue
$16.5M
Customers
-
Year founded
2010
Funding
$20.6M
Team size
19
Growth
-
5
Infoplus

Saint Louis, Missouri, United States

Infoplus is a powerful yet simple warehouse, inventory management, shipping software for e-Commerce and 3PL warehouses, retailers, distributors, and wholesalers.

Revenue
$15M
Customers
-
Year founded
2013
Funding
-
Team size
11
Growth
-
6
Native Pet

Saint Louis, MO, United States

Native Pet is a pet food and nutrition company that makes organic, highly effective, and limited-ingredient pet supplements for dogs and cats.

Revenue
$13.4M
Customers
-
Year founded
2017
Funding
-
Team size
55
Growth
-
7
US Cloud

Saint Louis, Missouri, United States

Provides reputable Microsoft enterprise support to clients world-wide. Enables Microsoft Premier (Unified) Support customers to enjoy ultra-responsive support from US citizens, saving 30-60% on support costs and freeing up funds to drive innovation

Revenue
$10M
Customers
-
Year founded
2006
Funding
-
Team size
124
Growth
-
8
Textel

Saint Louis, Missouri, United States

Developer of a carrier-grade texting platform designed to provide landline and toll-free texting services. The company offers direct network connectivity and intuitive cloud-based software with an enterprise-grade API and allows businesses to use any computer or mobile device for securely and reliably reaching their customers, enabling businesses to boost workplace productivity by supporting real human conversations at scale across any device.

Revenue
$6.8M
Customers
-
Year founded
2014
Funding
$5M
Team size
68
Growth
86.42%
9
DiningRD

Saint Louis, Missouri, United States

Dietary software company improving the lives of seniors by nurturing joy through food, offering comprehensive nutritional programs for senior living

Revenue
$6M
Customers
-
Year founded
1994
Funding
-
Team size
208
Growth
-
10
Gateway X

Saint Louis, Missouri, United States

Gateway X is a holding company that builds, buys and invests in market-leading DTC (direct to consumer) companies. Our purpose is to help people learn, grow and be the best versions of themselves through the journey of entrepreneurship. We value being fast, data-driven, customer centric and adaptable in our approach. We are committed to building one of the most important companies in the DTC revolution. We will be a profitable, long-term organization with an extraordinary culture and several unique winning brands.

Revenue
$4.8M
Customers
-
Year founded
2021
Funding
-
Team size
8
Growth
-
Saint Louis, United States SaaS Companies | GetLatka