Top 29 SaaS Companies in Waltham, United States, May 2026

Waltham, Massachusetts, United States

OpenClinica accelerates clinical trials by automating data acquisition through its software-as-a-service platform. Offering a secure bridge between healthcare and research, OpenClinica is trusted by the world’s foremost life science companies, academic institutions, and government entities and has been used in more than 10,000 studies involving over five million patients. OpenClinica is proud to support hundreds of small, midsize and large research organizations spanning biotech, pharma, medical device manufacturing and contract research organizations. Learn more at openclinica.com or email us at [email protected]

Waltham, Massachusetts, United States

Nobl9 Service Level Objective platform connects your reliability metrics to business goals via a modern engineering workflow.

Waltham, Massachusetts, United States

Provider of end-to-end infrastructure software designed to help consumers to access content anytime, on any device and packaged in ways that satisfy their interests. The company infrastructure software transforms the internet and other unmanaged IP connections into broadcast-quality and global delivery networks for live video, enabling clients to have transition from capital intensive, rigid broadcasting environments to new, dynamic, virtualized, and cost-effective operations.