Top 45 SaaS Companies in Durham, United States, May 2026

Durham, North Carolina, United States

Recover from any outage in 10 minutes or less.

Durham, North Carolina, United States

We use robots to build houses.

Durham, North Carolina, United States

Developer of healthcare education platform designed to address the inefficiencies that result from using too many systems to do too many things. The company's platform features course management, curriculum mapping, assessment and evaluations to patient encounter logs and lotteries, faculty effort tracking, personalized calendar and other related features that help to easily create and manage users and groups, rollover courses with just a few clicks, quickly import and export data and have access to events, courses and menus with role-based security model, enabling clients to enhance and develop their skills and expand their career.

Durham, North Carolina, United States

Built by Clinicians. Engineered for Value-Based Care. Revel Ai is an AI-powered care orchestration platform created by orthopedic surgeons and AI specialists. We streamline clinical workflows, enhance patient outcomes and empower providers to deliver value-based musculoskeletal care.

Durham, North Carolina, United States

Provider of patient billing and payment system created to deliver products and services designed for today's healthcare needs. The company develops a cloud-based patient billing and payment platform that automatically posts those payments to the proper balances in user system, just like your insurance payments, collect more payments and eliminate the time-consuming and manual steps without disrupting workflow, offering patients a simple way to manage their healthcare-related financial obligations.

Durham, North Carolina, United States

Shoeboxed is the industry leader in online receipt and business document management. Our mission is to save small business owners time and money by serving as the bridge between paperwork and dozens of powerful accounting, bookkeeping, tax prep and CRM tools. Shoeboxed scans and organizes receipts, bills and other financial documents to streamline accounting, automate bookkeeping and make tax season a breeze. We also scan and organize business cards to capture sales leads and build email marketing lists. Users can submit documents through our Magic Envelope™ prepaid mail-in service, using one of their free iPhone or Android apps, with any Fujitsu ScanSnap or HP web-connected printer, or by email. Shoeboxed partners with such companies as: Wave Accounting, Evernote, Xero, FreshBooks, Outright, Bill.com, Intuit, SmartVault, Fujitsu, and HP.

Durham, North Carolina, United States

Say goodbye to compliance anxiety with a tried and tested platform that increases your chance of winning new business, securing investment or securing exit. Picture this: You have been given the task of achieving compliance for ISO 27001, SOC 2, GDPR, or NHS DSPT certification for your business. Instead of pulling your hair out, you log into Hicomply's slick SaaS platform and boom - 90% of the work is already done for you. But wait, there's more: Real-time risk monitoring? Check. Automated task distribution? Check. Asset management that doesn't make you want to cry? Absolutely. And the best part? Hicomply isn't just another pretty face. It's built by Founders who've been in the trenches and know your pain. One more thing, Hicomply customers boast a 100% audit pass rate. That's right, 100%. No typo. But don't just take our word for it. Companies using Hicomply are seeing: 5x ROI on average Increased sales after certification Dramatically reduced time to certification. Dream of welcoming the auditors in with open arms? Hicomply's got your back. Don't let compliance be the anchor dragging your business down. Let Hicomply be the rocket fuel that propels you forward. Book a demo, you don't have to do this alone ....

Durham, North Carolina, United States

Create, manage, and track your email marketing — without leaving Shopify.

Durham, NC, United States

A BuildSense client once expressed, “The BuildSense team is not just designers and builders of homes, they are builders of dreams.” We believe the most important products we build are relationships. Understanding and respecting clients’ wants and needs forms the true foundation for a memorable home. At BuildSense, professional training and broad experience provide a full understanding of what it takes to deliver a delightful, healthy, and exceptional custom home or renovation. Working with our in-house architecture staff or in cooperation with partner designers, BuildSense makes it possible for clients to realize their dreams with focused coordination and cost analysis from early planning through construction. Start your relationship with the BuildSense team today. Listen. Plan. Design. Build.

Durham, North Carolina, United States

Data Decisions Group (DDG) brings together decades of expertise in consumer data, advanced analytics, and marketing research to deliver unmatched marketing and data solutions. Formed through the merger of three innovative companies — Web Decisions Group (consumer data and data processing, founded in 2012), Reach Analytics (proprietary machine learning modeling platform, founded in 2013), and FGI Research and Analytics (custom primary marketing research, founded in 1981) — DDG combines deep industry knowledge with cutting-edge technology. DDQ is based in Durham, NC with additional offices in Dallas, TX