Top 45 SaaS Companies in Durham, United States, August 2026

Durham, North Carolina, United States

Percona is widely recognized as a world-class open source database software, support, and services company. The organization is dedicated to helping businesses make databases and applications run better through a unique combination of expertise and open source software. Percona works with numerous global brands across many industries creating a unified experience to monitor, manage, secure, and optimize database environments on any infrastructure. Percona equips organizations with the freedom to choose, the freedom to create, and the freedom to make a difference - helping them scale and innovate with speed as they grow. Databases run better with Percona.

Durham, North Carolina, United States

service management software for commercial service contractors

Durham, North Carolina, United States

low-code BPM and workflow automation platform

Durham, North Carolina, United States

Secure payment data management platform

Durham, North Carolina, United States

410 Medical is a medical device company dedicated to developing innovative products that enable clinicians to improve care for critically ill patients. Their primary focus includes developing technology for rapid infusion of fluids and blood products.

Durham, North Carolina, United States

Asteor is a software product company and proud to present two world leading software products – Techcello and Synergita

Durham, North Carolina, United States

Provider of a cloud-based online clinician marketplace designed to match clinicians with healthcare facilities. The company's on-demand job marketplace connects healthcare workers looking for a job change, like nurses, therapists and other caregivers, to short-term jobs by letting them join the facility pools they want to work in, see all available shift information and directly communicate with facility hiring managers if needed, enabling hospital staffs to check employment options and get recruited at preferred healthcare organizations.

Durham, North Carolina, United States

Kevel is transforming the retail media space with its cutting-edge, AI-driven ad tech infrastructure APIs that power the Retail Media Cloud®. This groundbreaking solution combines the power of AI insights with API-based technology, allowing multi-brand retailers to build dynamic, customizable ad platforms while maintaining full control of their first-party data. With Kevel, retailers can deliver personalized shopper experiences, optimize ad targeting, and unlock predictive insights to stay ahead in an ever-evolving market. Kevel's mission is rooted in the belief that every digital retailer should have the tools to create their own tailored ad platform, comparable to industry leaders like Amazon. Harnessing the power of AI for data-driven decision-making, Kevel has helped leading brands such as Chewy, The Home Depot, Dollar General, Sonae, Lyft, El Corte Ingles, Slickdeals, and others launch impactful retail media networks, fostering innovation and unlocking new revenue opportunities. Kevel has garnered numerous accolades, earning recognition as one of the leading 100 innovative tech start-ups driving the future of brand-to-consumer in 2023 and awarded the MarTech Breakthrough Award for best overall ad tech company in 2022. In 2024 Kevel was shortlisted as a finalist in the AdExchanger Awards for the Best Commerce Media Technology category, as well as The Digiday Technology Awards for the Best-E-Commerce Technology category. Learn more about Kevel and its AI-powered solutions at www.kevel.com.