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Top 6 SaaS Companies in Middleton, United States, May 2026

As of May 2026, there are 6 SaaS companies based in Middleton. They have combined revenues of $275.4M and employ 740 employees. They've raised $4.5M in capital and serve 6.5K customers combined.

Companies
6
Revenue
$275.4M
Funding
$4.5M
Employees
740

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Top SaaS Companies in Middleton

Showing 10 of 6 companies ranked by annual revenue.

1
Esker Inc

Middleton, Wisconsin, United States

Esker helps organizations eliminate paper and improve business processes by integrating on-premise and on-demand document automation with applications for higher efficiency in sales order processing, invoicing, accounts payable and purchasing to shorten order-to-cash and procure-to-pay cycles. Built on patented technology, Esker solutions address the challenges of manual document processing that limit an organization's ability to increase speed and accuracy, raise productivity, reduce complexity, control costs and improve customer satisfaction. Over the past two decades Esker has become a worldwide leader in document process automation with offices in North America, Europe, Australia and Asia, and partners in more than 80 countries. Learn more about Esker: https://www.esker.com Explore Career Opportunities: https://www.esker.com/careers/job-opportunities

Revenue
$235.2M
Customers
6K
Year founded
1985
Funding
-
Team size
567
Growth
24.74%
2
URLgenius

MIDDLETON, Wisconsin, United States

Specializing in mobile app linking with a cloud-based platform that creates seamless user experiences

Revenue
$13M
Customers
-
Year founded
2012
Funding
-
Team size
25
Growth
106.35%
3
Voximetry

Middleton, Wisconsin, United States

Voximetry helps clinicians maximize access to sophisticated patient-specific dosimetry while minimizing financial and technical risks. It is a healthtech software company specializing in commercialization of complex algorithms for personalized treatment planning in advanced-stage cancer patients.

Revenue
$11M
Customers
-
Year founded
2016
Funding
-
Team size
20
Growth
-
4
Polco

Middleton, Wisconsin, United States

Developer of a social platform intended to modernize interaction between citizens and government. The company's platform integrates local to national legislation with citizen voting and crowd-sourced political commentary, enabling local leaders to post and share online policy polls and surveys.

Revenue
$10.8M
Customers
500
Year founded
2015
Funding
$4.5M
Team size
79
Growth
85.34%
5
SciNote - Electronic Lab Notebook

Middleton, Wisconsin, United States

SciNote is a top-rated platform for researchers in industry, academic and federal labs, who need electronic lab notebook, inventory management and project management functionalities 📋 It is trusted by FDA and more than 70k scientists. Where it thrives? - SciNote helps you organize your scientific data + safely stores it in 1 place, manage your team and experiments, - suitable for Labs of any size, - guarantee full traceability with time stamps and Electronic Signatures, - CFR 21 /11 compliant! Who is it for? - Industry labs: Who need to meet compliance requirements across their organizations - R&D Growing labs: that want to set up a paperless lab and wish to run it efficiently - CROs and CMOs: that have to organize lab work across teams, locations and projects - Federal R&D labs going digital to streamline their processes - Academics: that need more flexibility, storage space and extra security for their data Interested in SciNote? Find your plan! --​> https://www.scinote.net/premium/

Revenue
$4.2M
Customers
-
Year founded
2015
Funding
-
Team size
38
Growth
-
6
AI Spins Inc

Middleton, Wisconsin, United States

At AI SPINS, we redefine possibilities by integrating cutting-edge AI solutions into your business strategy. Harnessing the transformative power of artificial intelligence, we pave the way for unparalleled advancements and breakthroughs. Navigating the intricate landscape of modern industries requires expertise...

Revenue
$1.2M
Customers
-
Year founded
-
Funding
-
Team size
11
Growth
-
Middleton, United States SaaS Companies | GetLatka