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Top 277 SaaS Companies in San Diego, United States, May 2026

As of May 2026, there are 277 SaaS companies based in San Diego. They have combined revenues of $3.6B and employ 23.7K employees. They've raised $2.1B in capital and serve 494.2M customers combined.

Companies
277
Revenue
$3.6B
Funding
$2.1B
Employees
23.7K

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Top SaaS Companies in San Diego

Showing 10 of 81 companies ranked by annual revenue.

1
Trestle Biotherapeutics

San Diego, California, United States

Bioengineered kidneys for patients with kidney failure

Revenue
$5M
Customers
-
Year founded
2020
Funding
-
Team size
2
Growth
-
2
Navaide

San Diego, California, United States

Consulting group of highly skilled and motivated industry experts providing financial and acquisition system integration, data analytics and enterprise solutions

Revenue
$5M
Customers
-
Year founded
2016
Funding
-
Team size
56
Growth
-
3
Lawcus- - Law Practice Management Software

San Diego, California, United States

Lawcus streamlines Legal Practice Management, CRM and Client Intake so you can focus on what truly matters: your clients!

Revenue
$5M
Customers
-
Year founded
2014
Funding
-
Team size
8
Growth
-
4
Pricing IO

San Diego, California, United States

Helps B2B SaaS companies accelerate growth

Revenue
$5M
Customers
-
Year founded
2019
Funding
-
Team size
10
Growth
-
5
CB Therapeutics

San Diego, California, United States

Fermentation-derived natural products to solve health problems

Revenue
$5M
Customers
-
Year founded
-
Funding
-
Team size
14
Growth
-
6
GoDeskless

San Diego, California, United States

GoDeskless’s Innovative AI-powered, Mobile-First approach has revolutionized field services. In today’s “Economy of Convenience”, consumers and businesses demand instant access to products and services using their mobile devices. With GoDeskless, consumers enjoy a faster and more convenient experience of scheduling a service and Service Providers are equipped to respond and resolve customer requests much faster with an AI-powered, ‘mobile-first’ customer engagement solution. Typical areas of value impact are 20% decrease in Time to Resolutions (TTR), 20% increase in First Call Resolutions (FTR), 15% decrease in support costs, and a 25% average increase in customer satisfaction leading to a material increase in customer loyalty and retention. Convenience, speed and personalization are key and GoDeskless is leading the future of field service management.

Revenue
$4.8M
Customers
-
Year founded
2015
Funding
-
Team size
44
Growth
-
7
BriteVox

San Diego, California, United States

Marketing agency specializing in customer acquisition for a range of organizations that help create recurring revenue streams

Revenue
$4.7M
Customers
-
Year founded
2018
Funding
-
Team size
43
Growth
-
8
Tiled

San Diego, California, United States

Tiled empowers brands to take underperforming sales and marketing assets and turn them into interactive experiences that drive engagement and deliver insight. Want to learn more? See one of our microapps in action: https://s.tiled.co/1V_Uju5/losing-sales Simply import your design assets, including images, video, and audio, into our intuitive builder to assign interactive elements and publish to your team for instant viewing on desktop and mobile devices. With Tiled, you can create an unlimited number of public and private microapps equipped with security, permissions and user management to control who has access to your content. Metrics deliver insights on activity, summarizing when and where viewers spent their time, so you can prioritize your outreach efforts. From sales pitches to company playbooks, recruiting material to training courses, Tiled is the simplest way to make your content captivating and insightful.

Revenue
$4.7M
Customers
-
Year founded
2016
Funding
-
Team size
31
Growth
-
9
Chalk Digital

San Diego, California, United States

Chalk Digital is an innovative ad tech company, who is disrupting the way businesses can take advantage of mobile advertising to promote their brand, products, services and events. Chalk Digital’s Instant Mobile Ad Platform helps you create and launch your own mobile ad campaign in just a few minutes with precision, location, and audience targeting options. Chalk Digital provides a simple yet powerful solution to not only create, but also display your mobile ad campaign to potentially thousands of mobile consumers. Chalk’s ad creation tool helps you build a professional mobile banner ad in a manner of minutes. Then using its mobile location services technology, Chalk displays your mobile ad campaign to mobile consumers who are within your targeted area. Using Chalk Digital’s Instant Mobile Ad Platform you are able to reach mobile consumers across thousands of mobile apps around the world, or even just in your neighborhood.

Revenue
$4.4M
Customers
-
Year founded
2012
Funding
-
Team size
40
Growth
-
10
Astrya Global

San Diego, California, United States

An agency specializing in mental and behavioral health care staffing, bridging the gap between health care professionals and employers

Revenue
$4.1M
Customers
-
Year founded
2014
Funding
-
Team size
50
Growth
-91.49%