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Top 3 Medical Practice Management Software Companies $100M+ Revenue (August 2026)

As of August 2026, Latka tracks 3 medical practice management software companies with $100M+ in annual revenue. They have combined revenues of $1.2B and employ 7.9K people. They have raised $739M and serve 168K customers combined.

Every company below sells medical practice management software to other businesses and is ranked by its most recent annual revenue. Revenue, funding, headcount and customer figures come from CEO interviews on the Latka podcast, public company filings, and Latka estimates where a company has not disclosed a number.

What Medical Practice Management Software Companies do

Medical Practice Management Software encompasses a range of digital solutions designed to streamline operations within healthcare practices. This category includes tools for appointment scheduling, patient registration, billing, and efficient management of clinical workflows. By integrating various administrative and clinical processes, these software systems help medical practitioners enhance their service delivery while optimizing operational efficiency. Typical features of medical practice management software include patient portals for appointment management, electronic health record (EHR) integration, billing automation, and reporting capabilities. These functions support administrators, physicians, and office staff in maintaining smooth workflows, ensuring accurate patient records, and improving overall patient care experiences. The primary users include healthcare providers ranging from small practices to larger medical groups, focusing on both operational management and patient interactions.

Companies
3
Revenue
$1.2B
Funding
$739M
Employees
7.9K

Filters

Sorting: Highest -> Lowest

Filters

Top Medical Practice Management Software Companies $100M+ Revenue

Showing 3 of 3 companies ranked by annual revenue.

1eClinicalWorks logo
eClinicalWorks

Westborough, Massachusetts, United States

a medical practice platform intended to remove the operational burden faced by medical professionals in private practice.

Revenue
$1B
Year founded
1999
Team size
6.5K
2Tebra logo
Tebra

Corona del Mar, California, United States

The world of medicine is forever evolving, with new demands and challenges around every corner. We're always looking ahead to bring tomorrow's solutions to today's providers. Some might call it foresight or innovation. We call it Tebra. Today we’re helping practices thrive with solutions for practice operations and practice growth across our two products, Kareo and PatientPop. Together, they become the complete operating system for practice success.

Revenue
$112.2M
Customers
150K
Year founded
2021
Funding
$137M
Team size
1K
3Janeapp logo
Janeapp

North Vancouver, British Columbia, Canada

practice management software for health and wellness professionals

Revenue
$100M
Customers
18K
Year founded
2012
Funding
$602M
Team size
340

Frequently asked questions about Medical Practice Management Software Companies $100M+ Revenue

How many medical practice management software companies with $100M+ in annual revenue are there?

Latka tracks 3 medical practice management software companies with $100M+ in annual revenue. Together they generate $1.2B in annual revenue and employ 7.9K people.

Which medical practice management software company with $100M+ in annual revenue is the largest?

eClinicalWorks is the largest, with $1B in annual revenue, founded in 1999.

How much revenue does a typical medical practice management software company with $100M+ in annual revenue make?

The average medical practice management software company in this list makes $404.1M a year, across 3 companies with reported revenue. They serve 168K customers combined.

Who are the leading Medical Practice Management software vendors with $100M+ in annual revenue?

Ranked by annual revenue, the leaders are eClinicalWorks, Tebra and Janeapp.

How much funding have medical practice management software companies with $100M+ in annual revenue raised?

The 3 medical practice management software companies with $100M+ in annual revenue tracked here have raised $739M in disclosed funding between them.

Related Vertical Industry Software categories

Inclusion Criteria

- Must provide features for appointment scheduling and patient registration. - Must automate billing and insurance claims processing. - Must integrate with electronic health records (EHR) systems. - Must offer reporting and analytics capabilities for practice performance. - Must enhance patient engagement through a patient portal. - Not just a billing software; must also support clinical operations management.