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Top 50 Medical Practice Management Software Companies (August 2026)

As of August 2026, Latka tracks 94 medical practice management software companies. They have combined revenues of $2.1B and employ 15.3K people. They have raised $1.1B and serve 245.4M customers combined.

Every company below sells medical practice management software to other businesses and is ranked by its most recent annual revenue. Revenue, funding, headcount and customer figures come from CEO interviews on the Latka podcast, public company filings, and Latka estimates where a company has not disclosed a number.

What Medical Practice Management Software Companies do

Medical Practice Management Software encompasses a range of digital solutions designed to streamline operations within healthcare practices. This category includes tools for appointment scheduling, patient registration, billing, and efficient management of clinical workflows. By integrating various administrative and clinical processes, these software systems help medical practitioners enhance their service delivery while optimizing operational efficiency. Typical features of medical practice management software include patient portals for appointment management, electronic health record (EHR) integration, billing automation, and reporting capabilities. These functions support administrators, physicians, and office staff in maintaining smooth workflows, ensuring accurate patient records, and improving overall patient care experiences. The primary users include healthcare providers ranging from small practices to larger medical groups, focusing on both operational management and patient interactions.

Companies
94
Revenue
$2.1B
Funding
$1.1B
Employees
15.3K

Filters

Sorting: Highest -> Lowest

Filters

Top Medical Practice Management Software Companies by revenue

Showing 10 of 94 companies ranked by annual revenue.

1eClinicalWorks logo
eClinicalWorks

Westborough, Massachusetts, United States

a medical practice platform intended to remove the operational burden faced by medical professionals in private practice.

Revenue
$1B
Year founded
1999
Team size
6.5K
2Tebra logo
Tebra

Corona del Mar, California, United States

The world of medicine is forever evolving, with new demands and challenges around every corner. We're always looking ahead to bring tomorrow's solutions to today's providers. Some might call it foresight or innovation. We call it Tebra. Today we’re helping practices thrive with solutions for practice operations and practice growth across our two products, Kareo and PatientPop. Together, they become the complete operating system for practice success.

Revenue
$112.2M
Customers
150K
Year founded
2021
Funding
$137M
Team size
1K
3Janeapp logo
Janeapp

North Vancouver, British Columbia, Canada

practice management software for health and wellness professionals

Revenue
$100M
Customers
18K
Year founded
2012
Funding
$602M
Team size
340
4ClinicMind logo
ClinicMind

Clearwater, Florida, United States

ClinicMind empowers healthcare practice owners with one easy-to-use platform for full-cycle patient care, from intake to billing and beyond.

Revenue
$89.9M
Year founded
2005
Team size
341
5Medicus IT logo
Medicus IT

Alpharetta, Georgia, United States

Offers scalable, tangible IT solutions for all types of practices and health care organizations

Revenue
$73.1M
Year founded
2007
Team size
247
6RXNT logo
RXNT

Annapolis, Maryland, United States

Founded in 1999 and headquartered in Maryland, RXNT has built integrated, customizable, cloud-based clinical and practice management software that empowers providers to improve patient outcomes and streamline their business. Our innovative solutions support thousands of health providers of all specialties and sizes. Using our software, more than 100M prescriptions have been transmitted since our founding and over $300M in claims are processed annually.

Revenue
$54M
Year founded
1999
Team size
135
Growth
28.57%
7Bizmatics: A Harris Computer Company logo
Bizmatics: A Harris Computer Company

Niagara Falls, New York, United States

PrognoCIS, a leading EHR company provides clinical and business productivity software and services to medical practices & multi-specialties. Our cloud-based application, PrognoCIS is a fully-integrated solution comprising EHR, Telemedicine, Practice Management, Medical Billing, RCM, Patient Engagement tools, and more. Built on multi-tier Internet architecture, PrognoCIS EHR supports all major specialties and has fully customizable templates. The integrated architecture supports common databases for all Prognocis products to ensure seamless, real-time information flow between EHR and Billing. PrognoCIS is available both as an ASP service or an in-house Client-Server solution. PrognoCIS EHR is HIPAA Compliant, ICD 10 enabled, and Meaningful Stage 2 Certified. It has unique, integrated, click-saving features to enhance productivity and create a seamless workflow. Thousands of healthcare professionals nationwide use PrognoCIS, providing best-in-class healthcare services and patient safety while managing revenues and profitability. For more details about Bizmatics, visit prognocis.com.

Revenue
$46.6M
Year founded
2002
Team size
424
8SimplePractice logo
SimplePractice

Santa Monica, California, United States

practice management software for health professionals

Revenue
$36.8M
Customers
44M
Year founded
2012
Team size
508
9PetalMD logo
PetalMD

Québec, Québec, Canada

PetalMD is an information technology and services company that develops online management, communication and planning tools for physicians. Its cloud-based application solutions allow healthcare professionals to schedule management, synchronize data and manage personal documents. The company was founded in 2009 and is headquartered in Québec, Canada. The company seeks to expand through mergers, acquisitions, and investments which would help the firm consolidate its presence in the industry.

Revenue
$35M
Customers
37K
Year founded
2009
Team size
309
10UltraLinq Healthcare Solutions logo
UltraLinq Healthcare Solutions

New York, New York, United States

Provider of an online platform for medical imaging, ultrasound, examination and reports. The company develops a cloud based platform that helps in reviewing, reporting, archiving and distributing medical imaging modalities.

Revenue
$32.9M
Year founded
2002
Team size
36

Frequently asked questions about Medical Practice Management Software Companies

How many medical practice management software companies are there?

Latka tracks 94 medical practice management software companies with reported revenue. Together they generate $2.1B in annual revenue and employ 15.3K people.

Which medical practice management software company is the largest?

eClinicalWorks is the largest, with $1B in annual revenue, founded in 1999.

How much revenue does a typical medical practice management software company make?

The average medical practice management software company in this list makes $22.2M a year, across 94 companies with reported revenue. They serve 245.4M customers combined.

Who are the leading Medical Practice Management software vendors?

Ranked by annual revenue, the leaders are eClinicalWorks, Tebra, Janeapp, ClinicMind and Medicus IT.

How much funding have medical practice management software companies raised?

The 94 medical practice management software companies tracked here have raised $1.1B in disclosed funding between them.

Related Vertical Industry Software categories

Inclusion Criteria

- Must provide features for appointment scheduling and patient registration. - Must automate billing and insurance claims processing. - Must integrate with electronic health records (EHR) systems. - Must offer reporting and analytics capabilities for practice performance. - Must enhance patient engagement through a patient portal. - Not just a billing software; must also support clinical operations management.